Resistance to anti-VEGF therapy in neovascular age-related macular degeneration: a comprehensive review

S Yang, J Zhao, X Sun - Drug design, development and therapy, 2016 - Taylor & Francis
As a progressive chronic disease, age-related macular degeneration (AMD) is the leading
cause of irreversible vision impairment worldwide. Experimental and clinical evidence has …

Review of retinal angiomatous proliferation or type 3 neovascularization

LA Yannuzzi, KB Freund, BS Takahashi - Retina, 2008 - journals.lww.com
Retinal angiomatous proliferation (RAP), recently termed “type 3 neovascularization,”
represents a distinct form of neovascularization in age-related macular degeneration. On the …

Do we need a new classification for choroidal neovascularization in age-related macular degeneration?

KB Freund, SA Zweifel, M Engelbert - Retina, 2010 - journals.lww.com
The introduction of intravitreal antivascular endo-thelial growth factor (VEGF) therapy for
neovascular age-related macular degeneration (AMD) has not only improved the quality of …

Type 3 neovascularization: the expanded spectrum of retinal angiomatous proliferation

KB Freund, IV Ho, IA Barbazetto, H Koizumi, K Laud… - Retina, 2008 - journals.lww.com
Background: Retinal angiomatous proliferation (RAP) is a distinct form of neovascularization
in patients with age-related macular degeneration. Lacking definitive sequential …

“Treat and extend” dosing of intravitreal antivascular endothelial growth factor therapy for type 3 neovascularization/retinal angiomatous proliferation

M Engelbert, SA Zweifel, KB Freund - Retina, 2009 - journals.lww.com
Purpose: The purpose of this study was to analyze long-term outcomes for the treatment of
type 3 neovascularization/retinal angiomatous proliferation using a “Treat and Extend” …

Inject and extend dosing versus dosing as needed: a comparative retrospective study of ranibizumab in exudative age-related macular degeneration

H Oubraham, SY Cohen, S Samimi, D Marotte… - Retina, 2011 - journals.lww.com
Purpose: The purpose of this study was to compare two strategies for retreatment with
ranibizumab in exudative age-related macular degeneration. Method: Two series of …

Retinal angiomatous proliferation

ASH Tsai, N Cheung, ATL Gan, GJ Jaffe… - Survey of …, 2017 - Elsevier
Retinal angiomatous proliferation (RAP) is a unique variant of neovascular age-related
macular degeneration. Published studies have estimated that up to 15% of patients with …

Retinal angiomatous proliferation: natural history and progression of visual loss

F Viola, A Massacesi, N Orzalesi, R Ratiglia… - Retina, 2009 - journals.lww.com
Purpose: To investigate the natural history and visual outcome in eyes with untreated retinal
angiomatous proliferation, a neovascular form of age-related macular degeneration …

Clinical evidence of intravitreal triamcinolone acetonide in the management of age-related macular degeneration

EM Becerra, F Morescalchi, F Gandolfo… - Current drug …, 2011 - ingentaconnect.com
Triamcinolone acetonide (TA) is one of the first pharmacologic compounds evaluated for the
treatment of choroidal neovascularization (CNV) secondary to age-related macular …

Intravitreal bevacizumab (Avastin) for retinal angiomatous proliferation

CB Meyerle, KB Freund, D Iturralde, RF Spaide… - Retina, 2007 - journals.lww.com
Objective: To evaluate the short-term visual acuity and anatomic responses after intravitreal
bevacizumab (Avastin, Genentech) treatment in patients with retinal angiomatous …