Candidiasis and Mechanisms of Antifungal Resistance

S Bhattacharya, S Sae-Tia, BC Fries - Antibiotics, 2020 - mdpi.com
Candidiasis can be present as a cutaneous, mucosal or deep-seated organ infection, which
is caused by more than 20 types of Candida sp., with C. albicans being the most common …

Application and synthesis of thiazole ring in clinically approved drugs

ZX Niu, YT Wang, SN Zhang, Y Li, XB Chen… - European Journal of …, 2023 - Elsevier
The development of heterocyclic derivatives has progressed considerably over the past few
decades, and many new agents of synthetic and natural origin have been produced. Among …

Practice guidelines for the diagnosis and management of aspergillosis: 2016 update by the Infectious Diseases Society of America

TF Patterson, GR Thompson III… - Clinical infectious …, 2016 - academic.oup.com
It is important to realize that guidelines cannot always account for individual variation among
patients. They are not intended to supplant physician judgment with respect to particular …

Next generation of fluorine-containing pharmaceuticals, compounds currently in phase II–III clinical trials of major pharmaceutical companies: new structural trends …

Y Zhou, J Wang, Z Gu, S Wang, W Zhu… - Chemical …, 2016 - ACS Publications
Fluoroorganic chemistry has become essential in the evolution of many different but
interconnected research fields. These include the development of new materials with a …

Isavuconazole versus voriconazole for primary treatment of invasive mould disease caused by Aspergillus and other filamentous fungi (SECURE): a phase 3 …

JA Maertens, II Raad, KA Marr, TF Patterson… - The Lancet, 2016 - thelancet.com
Background Isavuconazole is a novel triazole with broad-spectrum antifungal activity. The
SECURE trial assessed efficacy and safety of isavuconazole versus voriconazole in patients …

Mucormycosis

G Reid, JP Lynch III, MC Fishbein… - Seminars in respiratory …, 2020 - thieme-connect.com
Mucormycosis is an infection caused by a group of filamentous molds within the order
Mucorales. Infections may result from ingestion of contaminated food, inhalation of spores …

[PDF][PDF] Triazole antifungals: a review

LR Peyton, S Gallagher, M Hashemzadeh - Drugs Today, 2015 - researchgate.net
Invasive fungal infections and systemic mycosis, whether from nosocomial infection or
immunodeficiency, have been on an upward trend for numerous years. Despite …

Azole antifungals: 35 years of invasive fungal infection management

D Allen, D Wilson, R Drew, J Perfect - Expert review of anti-infective …, 2015 - Taylor & Francis
Prior to 1981, treatment options for invasive fungal infections were limited and associated
with significant toxicities. The introduction of ketoconazole marked the beginning of an era of …

[HTML][HTML] Current antifungal drugs and immunotherapeutic approaches as promising strategies to treatment of fungal diseases

S Nami, A Aghebati-Maleki, H Morovati… - Biomedicine & …, 2019 - Elsevier
Invasive candidiasis (IC) can affect individuals with various underlying diseases hospitalized
in different parts of hospitals. In recent decades, IC has caused 27–55% mortality in general …

[HTML][HTML] Cutaneous mucormycosis

AD Castrejón-Pérez, EC Welsh, I Miranda… - Anais brasileiros de …, 2017 - SciELO Brasil
Cutaneous mucormycosis is an emerging fungal infection caused by opportunistic fungi of
the phylum Glomeromycota. It is frequent in poorly controlled diabetic patients and …