Toxicity of amphetamines: an update

M Carvalho, H Carmo, VM Costa, JP Capela… - Archives of …, 2012 - Springer
Amphetamines represent a class of psychotropic compounds, widely abused for their
stimulant, euphoric, anorectic, and, in some cases, emphathogenic, entactogenic, and …

Critical Issues in BDNF Val66Met Genetic Studies of Neuropsychiatric Disorders

SJ Tsai - Frontiers in molecular neuroscience, 2018 - frontiersin.org
Neurotrophins have been implicated in the pathophysiology of many neuropsychiatric
diseases. Brain-derived neurotrophic factor (BDNF) is the most abundant and widely …

Effects of BDNF polymorphisms on brain function and behavior in health and disease

CJ Hong, YJ Liou, SJ Tsai - Brain research bulletin, 2011 - Elsevier
Brain-derived neurotrophic factor (BDNF), the most abundant neurotrophin in the brain,
serves an important role during brain development and in synaptic plasticity. Given its …

MicroRNA expression signature of methamphetamine use and addiction in the rat nucleus accumbens

MS Sim, T Soga, V Pandy, YS Wu, IS Parhar… - Metabolic Brain …, 2017 - Springer
Methamphetamine (METH) is a highly addictive psycho-stimulant that induces behavioral
changes due to high level of METH-induced dopamine in the brain. Nucleus accumbens …

BDNF deficiency and young-adult methamphetamine induce sex-specific effects on prepulse inhibition regulation

EE Manning, M Van Den Buuse - Frontiers in cellular neuroscience, 2013 - frontiersin.org
Brain-derived neurotrophic factor (BDNF) has been implicated in the pathophysiology of
schizophrenia, yet its role in the development of specific symptoms is unclear …

Genetics of methamphetamine use disorder: A systematic review and meta-analyses of gene association studies

AA Guerin, EJ Nestler, M Berk, AJ Lawrence… - Neuroscience & …, 2021 - Elsevier
Genetic susceptibility to methamphetamine use disorder is poorly understood. No twin or
adequately powered genome-wide association studies (GWASs) have been conducted …

A significant association between BDNF promoter methylation and the risk of drug addiction

X Xu, H Ji, G Liu, Q Wang, H Liu, W Shen, L Li, X Xie… - Gene, 2016 - Elsevier
As a member of the neurotrophic factor family, brain derived neurotrophic factor (BDNF)
plays an important role in the survival and differentiation of neurons. The aim of our work …

BDNF rs6265 Polymorphism and Drug Addiction: a Systematic Review and Meta-Analysis

BS Haerian - Pharmacogenomics, 2013 - Taylor & Francis
A majority of studies have shown a link between the common functional rs6265
polymorphism of the BDNF gene and susceptibility to drug dependence. However, the …

Association between the brain-derived neurotrophic factor Val66Met polymorphism and overweight/obesity in pediatric population

JD Martínez-Ezquerro, ME Rendón-Macías… - Archives of Medical …, 2017 - Elsevier
Background The brain-derived neurotrophic factor (BDNF) rs6265 (G196A; Val66Met) single
nucleotide polymorphism has been associated with BMI and obesity in distinct populations …

BDNF-deficient mice show reduced psychosis-related behaviors following chronic methamphetamine

EE Manning, AL Halberstadt… - International Journal of …, 2016 - academic.oup.com
Background: One of the most devastating consequences of methamphetamine abuse is
increased risk of psychosis. Brain-derived neurotrophic factor has been implicated in both …