Sodium channels implement a molecular leaky integrator that detects action potentials and regulates neuronal firing

MA Navarro, A Salari, JL Lin, LM Cowan, NJ Penington… - Elife, 2020 - elifesciences.org
Voltage-gated sodium channels play a critical role in cellular excitability, amplifying small
membrane depolarizations into action potentials. Interactions with auxiliary subunits and …

The Drosophila Gr28bD product is a non-specific cation channel that can be used as a novel thermogenetic tool

A Mishra, A Salari, BR Berigan, KC Miguel… - Scientific reports, 2018 - nature.com
Extrinsic control of single neurons and neuronal populations is a powerful approach for
understanding how neural circuits function. Adding new thermogenetic tools to existing …

Parameter optimization for ion channel models: Integrating new data with known channel properties

MA Navarro, M Amirshenava, A Salari… - … Methods for Estimating …, 2021 - Springer
Ion channels play a central role in membrane physiology, but to fully understand how they
operate, one must have accurate kinetic mechanisms. Estimating kinetics is not trivial when …

Approaches for Unveiling the Kinetic Mechanisms of Voltage Gated Ion Channels in Neurons

MA Navarro - 2019 - search.proquest.com
Ionic currents drive cellular function within all living cells to perform highly specific tasks. For
excitable cells, such as muscle and neurons, voltage-gated ion channels have finely tuned …

[引用][C] Neuroscience tools in novel contexts: developing thermogenetics in Drosophila and decoding autonomic activity in mouse major pelvic ganglion

B Berigan - 2022 - University of Missouri--Columbia

[引用][C] Mining the Drosophila gustatory receptor family for new thermosensitive proteins: basic science and tool development

M Amirshenava - 2021 - University of Missouri--Columbia