The peril of gene-targeted conservation

M Kardos, ABA Shafer - Trends in ecology & evolution, 2018 - cell.com
The genomics revolution has sparked interest in using our increased understanding of the
loci involved in phenotypic variation and adaptation to advance the conservation of …

The evolution of two transmissible cancers in Tasmanian devils

MR Stammnitz, K Gori, YM Kwon, E Harry, FJ Martin… - Science, 2023 - science.org
Tasmanian devils have spawned two transmissible cancer lineages, named devil facial
tumor 1 (DFT1) and devil facial tumor 2 (DFT2). We investigated the genetic diversity and …

An oral bait vaccination approach for the Tasmanian devil facial tumor diseases

AS Flies, EJ Flies, S Fox, A Gilbert… - Expert review of …, 2020 - Taylor & Francis
ABSTRACT Introduction: The Tasmanian devil (Sarcophilus harrisii) is the largest extant
carnivorous marsupial. Since 1996, its population has declined by 77% primarily due to a …

The origins and vulnerabilities of two transmissible cancers in Tasmanian devils

MR Stammnitz, THH Coorens, KC Gori, D Hayes, B Fu… - Cancer cell, 2018 - cell.com
Transmissible cancers are clonal lineages that spread through populations via contagious
cancer cells. Although rare in nature, two facial tumor clones affect Tasmanian devils. Here …

The ecology and evolution of wildlife cancers: Applications for management and conservation

R Hamede, R Owen, H Siddle, S Peck… - Evolutionary …, 2020 - Wiley Online Library
Ecological and evolutionary concepts have been widely adopted to understand host–
pathogen dynamics, and more recently, integrated into wildlife disease management …

The newly-arisen Devil facial tumour disease 2 (DFT2) reveals a mechanism for the emergence of a contagious cancer

A Caldwell, R Coleby, C Tovar, MR Stammnitz… - Elife, 2018 - elifesciences.org
Devil Facial Tumour 2 (DFT2) is a recently discovered contagious cancer circulating in the
Tasmanian devil (Sarcophilus harrisii), a species which already harbours a more …

Tracing the rise of malignant cell lines: Distribution, epidemiology and evolutionary interactions of two transmissible cancers in Tasmanian devils

S James, G Jennings, YM Kwon… - Evolutionary …, 2019 - Wiley Online Library
Emerging infectious diseases are rising globally and understanding host‐pathogen
interactions during the initial stages of disease emergence is essential for assessing …

The Australian roadkill reporting project—Applying integrated professional research and citizen science to monitor and mitigate roadkill in Australia

B Englefield, M Starling, B Wilson, C Roder… - Animals, 2020 - mdpi.com
Simple Summary Australia has no database of national roadkill. The current research project
fills that knowledge gap by developing a roadkill reporting application that enables …

Extracellular vesicle proteomes of two transmissible cancers of Tasmanian devils reveal tenascin-C as a serum-based differential diagnostic biomarker

C Espejo, R Wilson, E Willms, M Ruiz-Aravena… - Cellular and Molecular …, 2021 - Springer
Abstract The iconic Tasmanian devil (Sarcophilus harrisii) is endangered due to the
transmissible cancer Devil Facial Tumour Disease (DFTD), of which there are two …

Cathelicidin-3 associated with serum extracellular vesicles enables early diagnosis of a transmissible cancer

C Espejo, R Wilson, RJ Pye, JC Ratcliffe… - Frontiers in …, 2022 - frontiersin.org
The identification of practical early diagnostic biomarkers is a cornerstone of improved
prevention and treatment of cancers. Such a case is devil facial tumor disease (DFTD), a …