[HTML][HTML] Let-7 in cardiovascular diseases, heart development and cardiovascular differentiation from stem cells

MH Bao, X Feng, YW Zhang, XY Lou… - International journal of …, 2013 - mdpi.com
The let-7 family is the second microRNA found in C. elegans. Recent researches have found
it is highly expressed in the cardiovascular system. Studies have revealed the aberrant …

Systematic review of microRNA biomarkers in acute coronary syndrome and stable coronary artery disease

A Kaur, ST Mackin, K Schlosser, FL Wong… - Cardiovascular …, 2020 - academic.oup.com
The aim of this systematic review was to assess dysregulated miRNA biomarkers in
coronary artery disease (CAD). Dysregulated microRNA (miRNAs) have been shown to be …

MicroRNA: a new therapeutic strategy for cardiovascular diseases

S Samanta, S Balasubramanian, S Rajasingh… - Trends in cardiovascular …, 2016 - Elsevier
Myocardial infarction, atherosclerosis, and hypertension are the most common heart-related
diseases that affect both the heart and the blood vessels. Multiple independent risk factors …

[HTML][HTML] Circulatory miR-133b and miR-21 as novel biomarkers in early prediction and diagnosis of coronary artery disease

D Kumar, R Narang, V Sreenivas, V Rastogi, J Bhatia… - Genes, 2020 - mdpi.com
While coronary artery disease (CAD) has become a major threat worldwide, the timely
biomarker-based early diagnosis of CAD remains a major unmet clinical challenge. We …

[HTML][HTML] Circulating miR-30a, miR-195 and let-7b associated with acute myocardial infarction

G Long, F Wang, Q Duan, S Yang, F Chen, W Gong… - PloS one, 2012 - journals.plos.org
Background MicroRNAs (miRNAs) play key roles in diverse biological and pathological
processes, including the regulation of proliferation, apoptosis, angiogenesis and cellular …

Identification of maternal serum microRNAs as novel non-invasive biomarkers for prenatal detection of fetal congenital heart defects

S Zhu, L Cao, J Zhu, L Kong, J Jin, L Qian, C Zhu… - Clinica chimica acta, 2013 - Elsevier
Background Congenital heart defects (CHD) are the most common form of malformation
during embryonic development. Circulating miRNAs have recently been shown to serve as …

[HTML][HTML] HBL1 is a human long noncoding RNA that modulates cardiomyocyte development from pluripotent stem cells by counteracting MIR1

J Liu, Y Li, B Lin, Y Sheng, L Yang - Developmental cell, 2017 - cell.com
Cardiogenesis processes in human and animals have differential dynamics, suggesting the
existence of species-specific regulators during heart development. However, it remains a …

[HTML][HTML] A novel YY1-miR-1 regulatory circuit in skeletal myogenesis revealed by genome-wide prediction of YY1-miRNA network

L Lu, L Zhou, EZ Chen, K Sun, P Jiang, L Wang, X Su… - PloS one, 2012 - journals.plos.org
microRNAs (miRNAs) are non-coding RNAs that regulate gene expression post-
transcriptionally, and mounting evidence supports the prevalence and functional …

Role of circulating miRNAs as biomarkers in idiopathic pulmonary arterial hypertension: possible relevance of miR‐23a

I Sarrion, L Milian, G Juan, M Ramon… - Oxidative medicine …, 2015 - Wiley Online Library
Idiopathic pulmonary hypertension (IPAH) is a rare disease characterized by a progressive
increase in pulmonary vascular resistance leading to heart failure. MicroRNAs (miRNAs) are …

[HTML][HTML] The RNA-binding Protein TDP-43 Selectively Disrupts MicroRNA-1/206 Incorporation into the RNA-induced Silencing Complex*♦

IN King, V Yartseva, D Salas, A Kumar… - Journal of Biological …, 2014 - ASBMB
MicroRNA (miRNA) maturation is regulated by interaction of particular miRNA precursors
with specific RNA-binding proteins. Following their biogenesis, mature miRNAs are …