The protein-folding problem was first posed about one half-century ago. The term refers to three broad questions:(i) What is the physical code by which an amino acid sequence …
The widespread use of controlled molecular‐level motion in key natural processes suggests that great rewards could come from bridging the gap between the present generation of …
DJ Hill, MJ Mio, RB Prince, TS Hughes… - Chemical …, 2001 - ACS Publications
The breadth of structure and function displayed by the molecules of biology is remarkable. Considering that there are only three major biopolymer backbones (proteins, ribonucleic …
The “protein folding problem” consists of three closely related puzzles:(a) What is the folding code?(b) What is the folding mechanism?(c) Can we predict the native structure of a protein …
Bioinspired polymeric materials are attracting increasing attention due to significant advantages over their natural counterparts: the ability to precisely tune their structures over a …
The protein folding problem was first articulated as question of how order arose from disorder in proteins: How did the various native structures of proteins arise from interatomic …
D Seebach, AK Beck, DJ Bierbaum - Chemistry & biodiversity, 2004 - Wiley Online Library
The origins of our nearly ten‐year research program of chemical and biological investigations into peptides based on homologated proteinogenic amino acids are …
Z Huang, L Qiu, T Zhang, W Tan - Matter, 2021 - cell.com
In addition to critical biological roles, DNA is also considered an excellent engineering material with unique characteristics of high programmability and addressability. Recent …
In the course of evolution, Nature has developed a multitude of biomacromolecules tailored to deal with complicated tasks such as information storage, support of tissue, transport, and …