The downside of antimicrobial agents for wound healing

A Punjataewakupt, S Napavichayanun… - European Journal of …, 2019 - Springer
The use of topical antimicrobials is beneficial for infection control in wound care because
wound infection is the major cause of delayed healing. The advantages of topical over …

Reflections on the OECD guidelines for in vitro skin absorption studies

NB Hopf, C Champmartin, L Schenk, A Berthet… - Regulatory Toxicology …, 2020 - Elsevier
At the 8th conference of Occupational and Environmental Exposure of the Skin to Chemicals
(OEESC)(16–18 September 2019) in Dublin, Ireland, several researchers performing skin …

Antimicrobial efficacy of eucalyptus oil and 1, 8-cineole alone and in combination with chlorhexidine digluconate against microorganisms grown in planktonic and …

ER Hendry, T Worthington, BR Conway… - Journal of …, 2009 - academic.oup.com
Objectives Effective disinfection and antisepsis is pivotal in preventing infections within the
healthcare setting. Chlorhexidine digluconate (CHG) is a widely used disinfectant/antiseptic …

Curcumin loaded chitin nanogels for skin cancer treatment via the transdermal route

S Mangalathillam, NS Rejinold, A Nair… - Nanoscale, 2012 - pubs.rsc.org
In this study, curcumin loaded chitin nanogels (CCNGs) were developed using
biocompatible and biodegradable chitin with an anticancer curcumin drug. Chitin, as well as …

[HTML][HTML] Investigation of effect of 1, 8-cineole on antimicrobial activity of chlorhexidine gluconate

M Şimşek, R Duman - Pharmacognosy research, 2017 - ncbi.nlm.nih.gov
Background: Chlorhexidine belongs to a group of medicines called antiseptic antibacterial
agents. Chlorhexidine is commonly used for the care and clean off the skin, hands, and …

Development and evaluation of 5-fluorouracil loaded chitin nanogels for treatment of skin cancer

M Sabitha, NS Rejinold, A Nair, VK Lakshmanan… - Carbohydrate …, 2013 - Elsevier
This study focuses on development and evaluation of 5-fluorouracil (5-FU) loaded chitin
nanogels (FCNGs). It formed good, stable aqueous dispersion with spherical particles in 120 …

Comparison of the antimicrobial efficacy of povidone-iodine-alcohol versus chlorhexidine-alcohol for surgical skin preparation on the aerobic and anaerobic skin flora …

D Dörfel, M Maiwald, G Daeschlein, G Müller… - … Resistance & Infection …, 2021 - Springer
Background Cutibacterium acnes is part of the anaerobic skin microbiome and resides in
deeper skin layers. The organism is an agent of surgical site infections (SSI) in shoulder …

Development of gellan gum containing formulations for transdermal drug delivery: Component evaluation and controlled drug release using temperature responsive …

CA Carmona-Moran, O Zavgorodnya… - International journal of …, 2016 - Elsevier
Enhancing skin permeation is important for development of new transdermal drug delivery
formulations. This is particularly relevant for non-steroidal anti-inflammatory drugs (NSAIDs) …

Use of chlorhexidine preparations in total joint arthroplasty

J George, AK Klika, CA Higuera - Journal of bone and joint …, 2017 - jbji.copernicus.org
Prosthetic joint infection (PJI) is a serious complication after total joint arthroplasty (TJA).
Chlorhexidine is a widely used antiseptic because of its rapid and persistent action. It is well …

[HTML][HTML] Bacterial reservoir in deeper skin is a potential source for surgical site and biomaterial-associated infections

C Guarch-Pérez, M Riool, L de Boer, P Kloen… - Journal of Hospital …, 2023 - Elsevier
Background The origin of surgical site and biomaterial-associated infection is still elusive.
Micro-organisms contaminating the wound may come from the air in the operating theatre …