Modification of biopharmaceutical molecules by covalent conjugation of polyethylene glycol
(PEG) molecules is known to enhance pharmacologic and pharmaceutical properties of …

PEGylation has emerged as a promising adaptation in the architecture of nanodelivery
systems to improve their physicochemical properties, stability, circulation time, passive …

Since several decades, PEGylation is known to be the clinical standard to enhance
pharmacokinetics of biotherapeutics. In this study, we introduce polyglycerol (PG) of different …

Carbohydrate biopolymer of biocompatible biodegradable chitosan, currently become one
of the most usable polymer in medical and pharmaceutical sciences. In this regard a large …

With growing regulatory interest in ensuring the integrity and consistency of the higher order
structure of biopharmaceutical and vaccine products, validated methods will be required that …

A wide variety of hemoglobin-based oxygen carriers (HBOCs) have been designed for use
as red blood cell (RBC) substitutes in transfusion medicine, ex vivo organ perfusion, oxygen …

The prion protein (PrP) is an N-glycosylated protein attached to the outer leaflet of eukaryotic
cell membranes via a glycosylphosphatidylinositol (GPI) anchor. Different prion strains have …

PEGylation has been used as a strategy to enhance pharmacokinetic properties of
therapeutic proteins by pharmaceutical industry. Imaged CIEF (iCIEF) is the current industry …

Staphylokinase (SAK) is a profibrinolytic protein and can be used for therapy of acute
myocardial infarction and coronary thrombosis. However, SAK suffers from a short serum …

Protein–polymer conjugates have achieved tremendous attention in the last few years, since
their importance in diverse fields including drug delivery, biotechnology and …