There is a real consensus that new antibiotics are urgently needed and are the best chance
for combating antibiotic resistance. The phylum Actinobacteria is one of the main producers …

Microbial natural products have been one of the most important sources for the discovery of
potential new antibiotics. However, the decline in the number of new chemical scaffolds …

In recognition of many microorganisms ability to produce a variety of secondary metabolites
in parallel, Zeeck and coworkers introduced the term “OSMAC”(one strain many …

As the world recovers from the COVID-19 pandemic, concern remains for future potential
outbreaks because of the persisting effects of climate change, including the proliferation of …

Introduction: The marine environment is a very promising resource for natural product
research, with many of these reaching the market as new drugs, especially in the field of …

The mycelial bacterium Streptomyces is a workhorse for producing natural products, serving
as a key source of drugs and other valuable chemicals. However, its complicated life cycle …

Streptomyces spp. are prolific sources of valuable natural products (NPs) that are of great
interest in pharmaceutical industries such as antibiotics, anticancer chemotherapeutics …

Bacteria harbor an immense reservoir of potentially new and therapeutic small molecules in
the form of “silent” biosynthetic gene clusters (BGCs). These BGCs can be identified …

The need for a new antibiotic pipeline to confront threat imposed by resistant pathogens has
become a major global concern for human health. To confront the challenge there is a need …

Streptomyces sp. produces clinically important bioactive compounds with anticancer,
antiviral, and antibacterial properties. These compounds have important roles in various …