Transcription of eukaryotic protein-coding genes commences with the assembly of a
conserved initiation complex, which consists of RNA polymerase II (Pol II) and the general …

In eukaryotes, the core promoter serves as a platform for the assembly of transcription
preinitiation complex (PIC) that includes TFIIA, TFIIB, TFIID, TFIIE, TFIIF, TFIIH, and RNA …

We show that transcription factor IIH ERCC3 subunit, the DNA helicase responsible for
adenosine triphosphate (ATP)–dependent promoter melting during transcription initiation …

This book arose from the summer course in eukaryotic gene expression at Cold Spring
Harbor Laboratory, in which the authors served as course instructors from 1994 through …

Essential components of the eukaryotic transcription apparatus include RNA polymerase II,
a common set of initiation factors, and a Mediator complex that transmits regulatory …

Basal transcription factor TFIID comprises the TATA-box-binding protein, TBP, and
associated factors, the TAF II s. Previous studies have implicated TAF II 250 and TAF II 150 …

In vivo footprinting studies have shown that transcription factor binding sites for HNF3 and
GATA-4 are occupied on the albumin gene enhancer in embryonic endoderm, prior to the …

Under the vast umbrella of Plant Sciences resides a plethora of highly specialized fields.
Botanists, agronomists, horticulturists, geneticists, and physiologists each employ a different …

The predominant organizational theme by which the transcription machinery and chromatin
regulators are positioned within promoter regions or throughout genes in a genome is …

High‐resolution atomic force microscopy (AFM) and biochemical methods were used to
analyze the structure of Escherichia coli RNA polymerase· σ 70 (RNAP) open promoter …