Host-and microbiota-derived extracellular vesicles, immune function, and disease development

L Macia, R Nanan, E Hosseini-Beheshti… - International journal of …, 2019 - mdpi.com
Extracellular vesicles (EVs) are blebs of either plasma membrane or intracellular
membranes carrying a cargo of proteins, nucleic acids, and lipids. EVs are produced by …

Extracellular vesicles in parasitic diseases

A Marcilla, L Martin-Jaular, M Trelis… - Journal of …, 2014 - Taylor & Francis
Parasitic diseases affect billions of people and are considered a major public health issue.
Close to 400 species are estimated to parasitize humans, of which around 90 are …

Extracellular vesicles as emerging targets in cancer: Recent development from bench to bedside

K Wu, F Xing, SY Wu, K Watabe - … et Biophysica Acta (BBA)-Reviews on …, 2017 - Elsevier
Extracellular vesicles (EVs) have emerged as important players of cancer initiation and
progression through cell-cell communication. They have been recognized as critical …

Biogenesis and biological functions of extracellular vesicles in cellular and organismal communication with microbes

Y Fang, Z Wang, X Liu, BM Tyler - Frontiers in microbiology, 2022 - frontiersin.org
Extracellular vesicles (EVs) represent a prominent mechanism of transport and interaction
between cells, especially microbes. Increasing evidence indicates that EVs play a key role in …

Extracellular vesicles: mediators and biomarkers of pathology along CNS barriers

SH Ramirez, AM Andrews, D Paul… - Fluids and Barriers of the …, 2018 - Springer
Extracellular vesicles (EVs) are heterogeneous, nano-sized vesicles that are shed into the
blood and other body fluids, which disperse a variety of bioactive molecules (eg, protein …

Blood–brain barrier in cerebral malaria: pathogenesis and therapeutic intervention

G Nishanth, D Schlüter - Trends in parasitology, 2019 - cell.com
Cerebral malaria is a life-threatening complication of malaria caused by the parasite
Plasmodium falciparum. The growing problem of drug resistance and the dearth of new …

The immunological balance between host and parasite in malaria

K Deroost, TT Pham, G Opdenakker… - FEMS microbiology …, 2016 - academic.oup.com
Coevolution of humans and malaria parasites has generated an intricate balance between
the immune system of the host and virulence factors of the parasite, equilibrating maximal …

Chloramidine/bisindolylmaleimide-I-mediated inhibition of exosome and microvesicle release and enhanced efficacy of cancer chemotherapy

US Kosgodage, RP Trindade, PR Thompson… - International journal of …, 2017 - mdpi.com
Microvesicle (MV) release from tumour cells influences drug retention, contributing to cancer
drug resistance. Strategically regulating MV release may increase drug retention within …

Sending a message: extracellular vesicles of pathogenic protozoan parasites

AJ Szempruch, L Dennison, R Kieft… - Nature Reviews …, 2016 - nature.com
Parasitic unicellular eukaryotes use extracellular vesicles (EVs) as vehicles for intercellular
communication and host manipulation. By using various mechanisms to generate EVs and …

Malaria parasites both repress host CXCL10 and use it as a cue for growth acceleration

Y Ofir-Birin, H Ben Ami Pilo, A Cruz Camacho… - Nature …, 2021 - nature.com
Pathogens are thought to use host molecular cues to control when to initiate life-cycle
transitions, but these signals are mostly unknown, particularly for the parasitic disease …