The regulation of energy in the brain has garnered substantial attention in recent years due
to its significant implications in various disorders and aging. The brain's energy metabolism …

Background Altered brain energy metabolism is implicated in Alzheimer disease (AD).
Limited and conflicting studies on brain pH changes, indicative of metabolic alterations …

Fmr1 (fragile X messenger ribonucleoprotein 1)-knockout (KO) rats, modeling the human
Fragile X Syndrome (FXS), are of particular interest for exploring the ASD-like phenotype in …

Alzheimer's disease poses a significant global health challenge owing to the progressive
cognitive decline of patients and absence of curative treatments. The current therapeutic …

The creatine‐phosphocreatine cycle serves as a crucial temporary energy buffering system
in the brain, regulated by brain creatine kinase (CKB), in maintaining Adenosine …

Objective Although astrocytic pathology is a pathological hallmark of progressive
supranuclear palsy (PSP), its pathophysiological role remains unclear. This study aimed to …

Alzheimer's disease (AD) is a prototypical neurodegenerative disorder, predominantly
affecting individuals in the presenile and elderly populations, with an etiology that remains …

Alzheimer's disease (AD) is characterized by complex interactions between
neuropathological markers, metabolic dysregulation, and structural brain changes. In this …

What Is the Role of Lactate in Brain Metabolism, Plasticity, and Neurodegeneration? | Neurology
Skip to main content Skip to main content AAN.com AAN Publications Author Center About the …

Background: Hepatic ischemia-reperfusion injury (HIRI) is known to affect cognitive
functions, with particular concern for its impact on brain metabolic dynamics. Circadian …