Tissue engineering for clean meat production

T Ben-Arye, S Levenberg - Frontiers in Sustainable Food Systems, 2019 - frontiersin.org
Increasing public awareness of foodborne illnesses, factory farming, and the ecological
footprint of the meat industry, has generated the need for animal-free meat alternatives. In …

[HTML][HTML] Therapeutic vaccines for high-risk HPV-associated diseases

A Chabeda, RJR Yanez, R Lamprecht, AE Meyers… - Papillomavirus …, 2018 - Elsevier
Cancer is the second leading cause of death worldwide, and it is estimated that Human
papillomavirus (HPV) related cancers account for 5% of all human cancers. Current HPV …

Regulatory approval and a first‐in‐human phase I clinical trial of a monoclonal antibody produced in transgenic tobacco plants

JKC Ma, J Drossard, D Lewis, F Altmann… - Plant biotechnology …, 2015 - Wiley Online Library
Although plant biotechnology has been widely investigated for the production of clinical‐
grade monoclonal antibodies, no antibody products derived from transgenic plants have yet …

Improvements of plant protein functionalities by Maillard conjugation and Maillard reaction products

RR Naik, Y Wang, C Selomulya - Critical Reviews in Food Science …, 2022 - Taylor & Francis
Plant-derived protein research has gained attention in recent years due to the rise of health
concerns, allergenicity, trends toward vegan diet, food safety, and sustainability; but the …

CRISPR/Cas9‐mediated knockout of six glycosyltransferase genes in Nicotiana benthamiana for the production of recombinant proteins lacking β‐1,2‐xylose and …

J Jansing, M Sack, SM Augustine… - Plant Biotechnology …, 2019 - Wiley Online Library
Plants offer fast, flexible and easily scalable alternative platforms for the production of
pharmaceutical proteins, but differences between plant and mammalian N‐linked glycans …

Plant molecular farming: production of metallic nanoparticles and therapeutic proteins using green factories

R Mohammadinejad, A Shavandi, DS Raie… - Green chemistry, 2019 - pubs.rsc.org
Plants have had numerous biological, clinical, pharmaceutical and medicinal purposes for
many years; however, their use as a general platform for preparation of desired …

Techno-economic analysis of a transient plant-based platform for monoclonal antibody production

S Nandi, AT Kwong, BR Holtz, RL Erwin, S Marcel… - MAbs, 2016 - Taylor & Francis
Plant-based biomanufacturing of therapeutic proteins is a relatively new platform with a
small number of commercial-scale facilities, but offers advantages of linear scalability …

Alternative methods of vaccine delivery: an overview of edible and intradermal vaccines

E Criscuolo, V Caputo, RA Diotti… - Journal of …, 2019 - Wiley Online Library
Vaccines are recognized worldwide as one of the most important tools for combating
infectious diseases. Despite the tremendous value conferred by currently available vaccines …

High level production of monoclonal antibodies using an optimized plant expression system

AG Diamos, JGL Hunter, MD Pardhe… - … in Bioengineering and …, 2020 - frontiersin.org
Biopharmaceuticals are a large and fast-growing sector of the total pharmaceutical market
with antibody-based therapeutics accounting for over 100 billion USD in sales yearly …

Plant‐made oral vaccines against human infectious diseases—are we there yet?

HT Chan, H Daniell - Plant biotechnology journal, 2015 - Wiley Online Library
Although the plant‐made vaccine field started three decades ago with the promise of
developing low‐cost vaccines to prevent infectious disease outbreaks and epidemics …