The role of imaging in targeted delivery of nanomedicine for cancer therapy

P Li, D Wang, J Hu, X Yang - Advanced Drug Delivery Reviews, 2022 - Elsevier
Nanomedicines overcome the pharmacokinetic limitations of traditional drug formulations
and have promising prospect in cancer treatment. However, nanomedicine delivery in vivo is …

An updated review of folate-functionalized nanocarriers: A promising ligand in cancer

P Ebrahimnejad, AS Taleghani, K Asare-Addo… - Drug discovery today, 2022 - Elsevier
The uncontrolled release of drugs in conventional drug delivery systems has led to the
introduction of new nanotechnology-based drug delivery systems and the use of targeted …

Formulation strategies for folate-targeted liposomes and their biomedical applications

P Kumar, P Huo, B Liu - Pharmaceutics, 2019 - mdpi.com
The folate receptor (FR) is a tumor-associated antigen that can bind with folic acid (FA) and
its conjugates with high affinity and ingests the bound molecules inside the cell via the …

Folate-conjugated nanovehicles: Strategies for cancer therapy

B Farran, RC Montenegro, P Kasa, E Pavitra… - Materials Science and …, 2020 - Elsevier
Cancer theranostics represents a strategy that aims at combining diagnosis with therapy
through the simultaneous imaging and targeted delivery of therapeutics to cancer cells …

Current strategies for different paclitaxel-loaded Nano-delivery Systems towards therapeutic applications for ovarian carcinoma: A review article

AM Khalifa, MA Elsheikh, AM Khalifa… - Journal of Controlled …, 2019 - Elsevier
Ovarian carcinoma (OC) is one of the leading causes of death among gynecologic
malignancies all over the world. It is characterized by high mortality rate because of the lack …

Folate-mediated chemotherapy and diagnostics: an updated review and outlook

L Xu, Q Bai, X Zhang, H Yang - Journal of controlled release, 2017 - Elsevier
Folate receptor (FR) is highly expressed in many types of human cancers, and it has been
actively studied for developing targeted chemotherapy and diagnostic agents. Tremendous …

Folate receptor-targeted PLGA-PEG nanoparticles for enhancing the activity of genistein in ovarian cancer

A Patra, S Satpathy, PK Naik, M Kazi… - Artificial Cells …, 2022 - Taylor & Francis
Genistein (GEN), a natural isoflavone possesses a wide range of pharmacological
properties and nutraceutical applications. GEN has been studied for its anticancer activity …

Nanoparticle delivery systems to combat drug resistance in ovarian cancer

EM Miller, TM Samec, AA Alexander-Bryant - … Nanotechnology, Biology and …, 2021 - Elsevier
Due to the lack of early symptoms and difficulty of accurate diagnosis, ovarian cancer is the
most lethal gynecological cancer faced by women. First-line therapy includes a combination …

Actively targeted nanoparticles for drug delivery to tumor

Y Bi, F Hao, G Yan, L Teng, RJ Lee… - Current drug …, 2016 - ingentaconnect.com
Background: Nanomedicine is an emerging therapeutic modality. Nanoparticles (NPs) are
potential vehicles for delivery of anticancer therapeutics. NPs can be designed to facilitate …

Thermosensitive and mucoadhesive sol-gel composites of paclitaxel/dimethyl-β-cyclodextrin for buccal delivery

SG Choi, SE Lee, BS Kang, CL Ng, E Davaa, JS Park - PLoS One, 2014 - journals.plos.org
The purpose of this study was to develop a buccal paclitaxel delivery system using the
thermosensitive polymer Pluronic F127 (PF127) and the mucoadhesive polymer …