Cognitive and behavioural flexibility: neural mechanisms and clinical considerations

LQ Uddin - Nature Reviews Neuroscience, 2021 - nature.com
Cognitive and behavioural flexibility permit the appropriate adjustment of thoughts and
behaviours in response to changing environmental demands. Brain mechanisms enabling …

Environmental influences on the pace of brain development

UA Tooley, DS Bassett, AP Mackey - Nature Reviews Neuroscience, 2021 - nature.com
Childhood socio-economic status (SES), a measure of the availability of material and social
resources, is one of the strongest predictors of lifelong well-being. Here we review evidence …

Increased global integration in the brain after psilocybin therapy for depression

RE Daws, C Timmermann, B Giribaldi, JD Sexton… - Nature medicine, 2022 - nature.com
Psilocybin therapy shows antidepressant potential, but its therapeutic actions are not well
understood. We assessed the subacute impact of psilocybin on brain function in two clinical …

[HTML][HTML] The foundation and architecture of precision medicine in neurology and psychiatry

H Hampel, P Gao, J Cummings, N Toschi… - Trends in …, 2023 - cell.com
Neurological and psychiatric diseases have high degrees of genetic and pathophysiological
heterogeneity, irrespective of clinical manifestations. Traditional medical paradigms have …

Segregation, integration, and balance of large-scale resting brain networks configure different cognitive abilities

R Wang, M Liu, X Cheng, Y Wu… - Proceedings of the …, 2021 - National Acad Sciences
Diverse cognitive processes set different demands on locally segregated and globally
integrated brain activity. However, it remains an open question how resting brains configure …

A computational model of neurodegeneration in Alzheimer's disease

D Jones, V Lowe, J Graff-Radford, H Botha… - Nature …, 2022 - nature.com
Disruption of mental functions in Alzheimer's disease (AD) and related disorders is
accompanied by selective degeneration of brain regions. These regions comprise large …

Segregation of functional networks is associated with cognitive resilience in Alzheimer's disease

M Ewers, Y Luan, L Frontzkowski, J Neitzel, A Rubinski… - Brain, 2021 - academic.oup.com
Cognitive resilience is an important modulating factor of cognitive decline in Alzheimer's
disease, but the functional brain mechanisms that support cognitive resilience remain …

[HTML][HTML] Brain parcellation selection: An overlooked decision point with meaningful effects on individual differences in resting-state functional connectivity

NV Bryce, JC Flournoy, JFG Moreira, ML Rosen… - NeuroImage, 2021 - Elsevier
Over the past decade extensive research has examined the segregation of the human brain
into large-scale functional networks. The resulting network maps, ie parcellations, are now …

Effortless training of attention and self-control: mechanisms and applications

YY Tang, R Tang, MI Posner, JJ Gross - Trends in Cognitive Sciences, 2022 - cell.com
For the past 50 years, cognitive scientists have assumed that training attention and self-
control must be effortful. However, growing evidence suggests promising effects of effortless …

Functional networks of the brain: from connectivity restoration to dynamic integration

AE Hramov, NS Frolov, VA Maksimenko… - Physics …, 2021 - iopscience.iop.org
A review of physical and mathematical methods for reconstructing the functional networks of
the brain based on recorded brain activity is presented. Various methods are considered, as …