The vertebrate transcription factor NF-κB is induced by over 150 different stimuli. Active NF-
κB, in turn, participates in the control of transcription of over 150 target genes. Because a …

The airway epithelium acts as a frontline defense against respiratory viruses, not only as a
physical barrier and through the mucociliary apparatus but also through its immunological …

Ageing is the biggest risk factor for impaired cardiovascular health, with cardiovascular
disease being the cause of death in 40% of individuals over 65 years old. Ageing is …

The transcription factor NF-κB is activated in a range of human cancers and is thought to
promote tumorigenesis, mainly due to its ability to protect transformed cells from apoptosis …

A key component of cardiac ischemia–reperfusion injury (IRI) is the increased generation of
reactive oxygen species, leading to enhanced inflammation and tissue dysfunction in …

Several studies have demonstrated unequivocally that certain nonsteroidal anti‐
inflammatory drugs (NSAIDs) such as sodium salicylate, sulindac, ibuprofen, and …

Bovine respiratory syncytial virus (BRSV) belongs to the pneumovirus genus within the
family Paramyxoviridae and is a major cause of respiratory disease in young calves. BRSV …

Respiratory syncytial virus (RSV) is one of the commonest and most troublesome viruses of
infancy. It causes most cases of bronchiolitis, which is associated with wheezing in later …

Nuclear factor-κ B (NF-κB) is a family of DNA-binding protein factors that are required for
transcription of most proinflammatory molecules, including adhesion molecules, enzymes …

The transcription factor nuclear factor (NF)–κB controls the expression of numerous
respiratory syncytial virus (RSV)–inducible inflammatory and immunomodulatory genes …