Mass cytometry has revolutionized immunophenotyping, particularly in exploratory settings
where simultaneous breadth and depth of characterization of immune populations is needed …

Mass cytometry has become an important technique for the deep analysis of single cell
protein expression required for precision systems immunology. The ability to profile more …

SARS-CoV-2 infection and mRNA vaccination both elicit spike (S)-specific T cell responses.
To analyze how T cell memory from prior infection influences T cell responses to …

Tumor-specific T cells likely underpin effective immune checkpoint-blockade therapies. Yet,
most studies focus on Treg cells and CD8+ tumor-infiltrating lymphocytes (TILs). Here, we …

Neoantigens derived from somatic mutations in cancer cells can induce antigen‐specific T‐
cell immune response for cancer immunotherapy. However, the 3D models for assessing …

Cutaneous T cell lymphomas (CTCLs) are skin cancers with poor survival rates and limited
treatments. While immunotherapies have shown some efficacy, the immunological …

Objectives Lymphoepithelioma‐like carcinoma (LELC) is an uncommon lung cancer,
typically observed in young, non‐smoking Asian populations. LELC is associated with …

Background In biomedical research, achieving single-cell resolution in investigation of
cellular systems is of paramount importance. Ongoing research efforts to explore and …

Hantaan virus (HTNV), the causative pathogen of hemorrhagic fever with renal syndrome
(HFRS), is a negative RNA virus belonging to the Orthohantaviridae family. HTNV envelope …

Placentation presents immune conflict between mother and fetus, yet in normal pregnancy
maternal immunity against infection is maintained without expense to fetal tolerance. This is …