High-resolution analysis of the human retina miRNome reveals isomiR variations and novel microRNAs

M Karali, M Persico, M Mutarelli… - Nucleic acids …, 2016 - academic.oup.com
MicroRNAs play a fundamental role in retinal development and function. To characterise the
miRNome of the human retina, we carried out deep sequencing analysis on sixteen …

Zebrafish retinal defects induced by ethanol exposure are rescued by retinoic acid and folic acid supplement

P Muralidharan, S Sarmah, JA Marrs - Alcohol, 2015 - Elsevier
Abstract Fetal Alcohol Spectrum Disorder (FASD) is caused by prenatal alcohol exposure,
producing craniofacial, sensory, motor, and cognitive defects. FASD is highly prevalent in …

Complex cardiac defects after ethanol exposure during discrete cardiogenic events in zebrafish: prevention with folic acid

S Sarmah, JA Marrs - Developmental Dynamics, 2013 - Wiley Online Library
Background: Fetal alcohol spectrum disorder (FASD) describes a range of birth defects
including various congenital heart defects (CHDs). Mechanisms of FASD‐associated CHDs …

[HTML][HTML] Long noncoding RNA SMAD5-AS1 acts as a microRNA-106a-5p sponge to promote epithelial mesenchymal transition in nasopharyngeal carcinoma

YJ Zheng, JY Zhao, TS Liang, P Wang, J Wang… - The FASEB …, 2019 - ncbi.nlm.nih.gov
Nasopharyngeal carcinoma (NPC) is a malignant epithelial cancer of the head and neck
with high prevalence in southern China, which is accompanied by notable invasiveness and …

An analytical enrichment‐based review of structural genetic studies on keratoconus

Y Panahi, A Azimi, M Naderi, K Jadidi… - Journal of Cellular …, 2019 - Wiley Online Library
Keratoconus is a progressive bilateral corneal protrusion that leads to irregular astigmatism
and impairment of vision. Keratoconus is an etiologically heterogeneous corneal dystrophy …

Changes in DNA methylation hallmark alterations in chromatin accessibility and gene expression for eye lens differentiation

J Disatham, L Brennan, X Jiao, Z Ma… - Epigenetics & …, 2022 - Springer
Background Methylation at cytosines (mCG) is a well-known regulator of gene expression,
but its requirements for cellular differentiation have yet to be fully elucidated. A well-studied …

Single-cell resolution of MET-and EMT-like programs in osteoblasts during zebrafish fin regeneration

WJ Tang, CJ Watson, T Olmstead, CH Allan, RY Kwon - Iscience, 2022 - cell.com
Zebrafish regenerate fin rays following amputation through epimorphic regeneration, a
process that has been proposed to involve the epithelial-to-mesenchymal transition (EMT) …

Ethanol exposure disrupts extraembryonic microtubule cytoskeleton and embryonic blastomere cell adhesion, producing epiboly and gastrulation defects

S Sarmah, P Muralidharan, CL Curtis… - Biology …, 2013 - journals.biologists.com
Fetal alcohol spectrum disorder (FASD) occurs when pregnant mothers consume alcohol,
causing embryonic ethanol exposure and characteristic birth defects that include …

Retinal Wnt signaling defect in a zebrafish fetal alcohol spectrum disorder model

P Muralidharan, S Sarmah, JA Marrs - PLoS One, 2018 - journals.plos.org
Fetal alcohol spectrum disorder caused by prenatal alcohol exposure includes ocular
abnormalities (microphthalmia, photoreceptor dysfunction, cataracts). Zebrafish embryos …

Elsahy–Waters syndrome is caused by biallelic mutations in CDH11

FL Harms, S Nampoothiri, S Anazi… - American journal of …, 2018 - Wiley Online Library
Elsahy–Waters syndrome (EWS), also known as branchial–skeletal–genital syndrome, is a
distinct dysmorphology syndrome characterized by facial asymmetry, broad forehead …