The aim was to compare results of studies performed in different settings worldwide and
identify common therapeutic areas to allow for focused interventions, because off-label drug …

This review aims to give an updated overview of the worldwide situation of off-label and
unlicensed drug use in the paediatric field, also taking into account the safety of this kind of …

OBJECTIVES. The objectives were (1) to identify the drugs reported most commonly during
NICU care,(2) to examine how different methods of documenting drug use could influence …

The rise of quality improvement research and comparative effectiveness research in health
care settings constitutes progress toward the goal of what the Institute of Medicine has called …

Off‐label prescribing is the prescription of a registered medicine for a use that is not included
in the product information. The practice is common, with rates up to 40% in adults and up to …

BACKGROUND: Off-label drug use in children is common and potentially harmful. In most
previous off-label use research, authors studied hospitalized children, specific drug classes …

Background In the past two decades, many legislative and regulatory initiatives were taken
globally to improve drug use in children. However, children are still found to be prescribed …

Background and objective Clearance is an important pharmacokinetic concept for scaling
dosage, understanding the risks of drug-drug interactions and environmental risk …

Aims To examine the impact of off‐label and unlicensed (OLUL) prescribing on adverse
drug reactions (ADR s) causing unplanned admissions to a paediatric hospital. Methods …

OBJECTIVE: The aim of this study was to determine the frequency of off-label prescribing to
children at United States outpatient visits and to determine how drug class, patient age, and …