Chitosan nanoparticles as a promising tool in nanomedicine with particular emphasis on oncological treatment

J Sharifi-Rad, C Quispe, M Butnariu, LS Rotariu… - Cancer cell …, 2021 - Springer
The study describes the current state of knowledge on nanotechnology and its utilization in
medicine. The focus in this manuscript was on the properties, usage safety, and potentially …

Polysaccharide nanoparticles: From fabrication to applications

A Plucinski, Z Lyu, BVKJ Schmidt - Journal of Materials Chemistry B, 2021 - pubs.rsc.org
Polysaccharides have attracted considerable attention in a broad range of applications in
recent years, which is due to their remarkable features such as biocompatibility …

Novel biomaterial strategies for controlled growth factor delivery for biomedical applications

Z Wang, Z Wang, WW Lu, W Zhen, D Yang… - NPG Asia …, 2017 - nature.com
Growth factors (GFs) are soluble proteins secreted by cells that have the ability to regulate a
variety of cellular processes and tissue regeneration. However, their translation into clinical …

Functionalizing nanoparticles with biological molecules: developing chemistries that facilitate nanotechnology

KE Sapsford, WR Algar, L Berti, KB Gemmill… - Chemical …, 2013 - ACS Publications
Bionanotechnology has now become firmly established in its own right as one of the
principle and focused subdisciplines within nanotechnology.(1-10) Bionanotechnology can …

Polysaccharide‐based controlled release systems for therapeutics delivery and tissue engineering: from bench to bedside

T Miao, J Wang, Y Zeng, G Liu, X Chen - Advanced science, 2018 - Wiley Online Library
Polysaccharides or polymeric carbohydrate molecules are long chains of monosaccharides
that are linked by glycosidic bonds. The naturally based structural materials are widely …

Design of spherically structured 3D in vitro tumor models-Advances and prospects

LP Ferreira, VM Gaspar, JF Mano - Acta biomaterialia, 2018 - Elsevier
Three-dimensional multicellular tumor models are receiving an ever-growing focus as
preclinical drug-screening platforms due to their potential to recapitulate major physiological …

Enhanced MSC chondrogenesis following delivery of TGF-β3 from alginate microspheres within hyaluronic acid hydrogels in vitro and in vivo

L Bian, DY Zhai, E Tous, R Rai, RL Mauck, JA Burdick - Biomaterials, 2011 - Elsevier
Mesenchymal stem cells (MSCs) are being recognized as a viable cell source for cartilage
repair and members of the transforming growth factor-beta (TGF-β) superfamily are a key …

Growth factor and cytokine delivery systems for wound healing

JMD Legrand, MM Martino - Cold Spring Harbor …, 2022 - cshperspectives.cshlp.org
Skin wound healing is a highly coordinated process involving multiple tissue-resident and
recruited cell types. Cells within the wound microenvironment respond to key secreted …

[HTML][HTML] Glycosaminoglycan-based biomaterials for growth factor and cytokine delivery: Making the right choices

D Hachim, TE Whittaker, H Kim, MM Stevens - Journal of Controlled …, 2019 - Elsevier
Controlled, localized drug delivery is a long-standing goal of medical research, realization of
which could reduce the harmful side-effects of drugs and allow more effective treatment of …

[HTML][HTML] Vascular endothelial growth factor (VEGF) delivery approaches in regenerative medicine

N Beheshtizadeh, M Gharibshahian, M Bayati… - Biomedicine & …, 2023 - Elsevier
The utilization of growth factors in the process of tissue regeneration has garnered
significant interest and has been the subject of extensive research. However, despite the …