Networks are one of the most common ways to represent biological systems as complex sets
of binary interactions or relations between different bioentities. In this article, we discuss the …

Despite considerable progress in genome-and proteome-based high-throughput screening
methods and in rational drug design, the increase in approved drugs in the past decade did …

Abstract We present the Open Graph Benchmark (OGB), a diverse set of challenging and
realistic benchmark datasets to facilitate scalable, robust, and reproducible graph machine …

In Biocultural Creatures, Samantha Frost brings feminist and political theory together with
findings in the life sciences to recuperate the category of the human for politics. Challenging …

A central goal of systems biology is to elucidate the structural and functional architecture of
the cell. To this end, large and complex networks of molecular interactions are being rapidly …

Macromolecular complexes are essential to conserved biological processes, but their
prevalence across animals is unclear. By combining extensive biochemical fractionation …

Access to unified datasets of protein and genetic interactions is critical for interrogation of
gene/protein function and analysis of global network properties. BioGRID is a freely …

A fundamental challenge in human health is the identification of disease-causing genes.
Recently, several studies have tackled this challenge via a network-based approach …

Cytoscape is a free software package for visualizing, modeling and analyzing molecular and
genetic interaction networks. This protocol explains how to use Cytoscape to analyze the …

Determining the composition of protein complexes is an essential step toward
understanding the cell as an integrated system. Using coaffinity purification coupled to mass …