Electrochemical oxidative cross-coupling with hydrogen evolution reactions

Y Yuan, A Lei - Accounts of Chemical Research, 2019 - ACS Publications
Conspectus Oxidative cross-coupling has proved to be one of the most straightforward
strategies for forming carbon–carbon and carbon–heteroatom bonds from easily available …

COVID-19 molecular pathophysiology: acetylation of repurposing drugs

JH Lee, B Kanwar, A Khattak, J Balentine… - International Journal of …, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) induces immune-mediated
type 1 interferon (IFN-1) production, the pathophysiology of which involves sterile alpha …

DNA/BSA binding affinity studies of new Pd (II) complex with SS and NN donor mixed ligands via experimental insight and molecular simulation: Preliminary antitumor …

M Feizi-Dehnayebi, E Dehghanian… - Journal of Molecular …, 2021 - Elsevier
Due to the importance of metallo drugs that can bind to DNA and prohibit division of cancer
cells, a novel water-like palladium (II) complex,[Pd (phen)(proli-dtc)] NO 3 (phen= 1, 10 …

Transition-metal-and oxidant-free directed anodic C–H sulfonylation of N, N-disubstituted anilines with sulfinates

YC Wu, SS Jiang, SZ Luo, RJ Song, JH Li - Chemical Communications, 2019 - pubs.rsc.org
A new, practical directed anodic C–H sulfonylation of N, N-disubstituted anilines with sodium
sulfinates for producing o-or p-amino arylsulfones and diarylsulfones is described …

4, 4′-Diaminodiphenyl sulfone (DDS) as an inflammasome competitor

J Lee, HK An, MG Sohn, P Kivela, S Oh - International journal of …, 2020 - mdpi.com
The aim of this study is to examine the use of an inflammasome competitor as a preventative
agent. Coronaviruses have zoonotic potential due to the adaptability of their S protein to …

Carbazole appended trans-dicationic pyridinium porphyrin finds supremacy in DNA binding/photocleavage over a non-carbazolyl analogue

A Das, TP Mohammed, R Kumar, S Bhunia… - Dalton …, 2022 - pubs.rsc.org
A carbazolyl appended trans-pyridyl porphyrin (1) was synthesized and its dicationic form 2
was obtained by methylation of the pyridyl group. Copper and zinc complexes of porphyrin 2 …

Specific treatment exists for SARS-CoV-2 ARDS

B Kanwar, CJ Lee, JH Lee - Vaccines, 2021 - mdpi.com
The COVID-19 pandemic, caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), seems to be difficult to overcome. A pandemic of such a scale has not been …

Structural analysis of biomacromolecules using circular dichroism spectroscopy

X Zhao, Y Wang, D Zhao - … Methods to Study Biomolecular Structure and …, 2023 - Elsevier
The chirality of biomacromolecules renders circular dichroism (CD) detection a method to
measure their multiscale structures. This chapter reviews the applications of CD …

A search for antiinflammatory therapies: Synthesis, in silico investigation of the mode of action, and in vitro analyses of new quinazolin‐2, 4‐dione derivatives targeting …

AH Abdelmonsef, MA Abdelhakeem… - Journal of …, 2022 - Wiley Online Library
Inflammation is the response of the body's immune system to harmful stimuli. The expression
of phosphodiesterase 4 enzyme (PDE4) was demonstrated in many inflammatory cells …

Repurposing of antimycobacterium drugs for COVID-19 treatment by targeting SARS CoV-2 main protease: An in-silico perspective

A Chakraborty, R Ghosh, SS Mohapatra, S Barik… - Gene, 2024 - Elsevier
The global mortality rate has been significantly impacted by the COVID-19 pandemic,
caused by the SARS CoV-2 virus. Although the pursuit for a potent antiviral is still in …