Vitiligo is an acquired hypopigmentation of the skin due to a progressive selective loss of
melanocytes; it has a prevalence of 1–2% and appears as rounded, well-demarcated white …

The events that convert adherent epithelial cells into individual migratory cells that can
invade the extracellular matrix are known collectively as epithelial-mesenchymal transition …

The disorder now known as vitiligo was first described by Claude Nicolas Le Cat in 1765. 1
However, the first specific consideration of a genetic component in vitiligo did not come until …

Melanocytes differentiate from the neural crest (NC), which is a transient population of cells
that delaminates from the neural tube and migrates extensively throughout the embryo …

Vitiligo is a complex disease in which autoimmune destruction of epidermal melanocytes
results in patches of depigmented white skin. Vitiligo has an estimated prevalence of about …

Generalized vitiligo (GV) is a complex disease in which patchy depigmentation results from
autoimmune loss of melanocytes from affected regions. Genetic analyses of GV span six …

Vitiligo is an acquired depigmenting disorder characterized by the loss of functioning
epidermal melanocytes because of multifactorial and overlapping pathogenetic …

Generalized vitiligo is an acquired disorder in which white patches of skin and overlying hair
result from autoimmune loss of melanocytes from involved areas. The autoimmune …

Vitiligo is an acquired disorder in which patches of depigmented skin and often overlying
hair, and mucous membranes, are the result of progressive autoimmune loss of melanocytes …

We previously carried out a genome-wide association study of generalized vitiligo (GV) in
non-Hispanic whites, identifying 13 confirmed susceptibility loci. In this study, we re …