Role of the Microbiome in Neonatal Infection: Pathogenesis and Implications for Management

C McGann, R Phyu, K Bittinger… - Clinics in …, 2024 - perinatology.theclinics.com
Globally, infections in the neonatal period remain a leading cause of pediatric morbidity and
mortality. 1 Sepsis prevalence and associated mortality increase with decreasing gestational …

Exploring the immunomodulatory potential of human milk: Aryl hydrocarbon receptor activation and its impact on neonatal gut health

NV Wieser, M Ghiboub, C Verseijden… - Nutrients, 2024 - mdpi.com
Several metabolites of the essential amino acid tryptophan have emerged as key players in
gut homeostasis through different cellular pathways, particularly through metabolites which …

Update to the Neonatal Early-Onset Sepsis Calculator Utilizing a Contemporary Cohort

MW Kuzniewicz, GJ Escobar, H Forquer, S Li… - …, 2024 - publications.aap.org
Video Abstract BACKGROUND AND OBJECTIVES The Kaiser Permanente Neonatal Early-
Onset Sepsis (EOS) Calculator has been an effective tool for risk stratification to safely …

Antibiotic use among extremely low birth-weight infants from 2009 to 2021: a retrospective observational study

DD Flannery, AZ Barboza, S Mukhopadhyay… - Archives of Disease in …, 2024 - fn.bmj.com
Objective To assess trends in antibiotic use across a large cohort of extremely low birth-
weight (< 1000 g; ELBW) infants admitted to academic and community neonatal intensive …