Review insights on salivary proteomics biomarkers in oral cancer detection and diagnosis

VR Umapathy, PM Natarajan, B Swamikannu - Molecules, 2023 - mdpi.com
Early detection is crucial for the treatment and prognosis of oral cancer, a potentially lethal
condition. Tumor markers are abnormal biological byproducts produced by malignant cells …

Epigenetic modifications and head and neck cancer: implications for tumor progression and resistance to therapy

RM Castilho, CH Squarize, LO Almeida - International journal of …, 2017 - mdpi.com
Head and neck squamous carcinoma (HNSCC) is the sixth most prevalent cancer and one
of the most aggressive malignancies worldwide. Despite continuous efforts to identify …

Serum, plasma and saliva biomarkers for head and neck cancer

LMRB Arantes, AC De Carvalho… - Expert review of …, 2018 - Taylor & Francis
Introduction: Head and neck squamous cell carcinoma (HNSCC) encompasses tumors
arising from several locations (oral and nasal cavities, paranasal sinuses, salivary glands …

The performance of an oral microbiome biomarker panel in predicting oral cavity and oropharyngeal cancers

Y Lim, N Fukuma, M Totsika, L Kenny… - Frontiers in cellular …, 2018 - frontiersin.org
The oral microbiome can play a role in the instigation and progression of oral diseases that
can manifest into other systemic conditions. These associations encourage the exploration …

Epigenetics of oral and oropharyngeal cancers (Review) Corrigendum in/10.3892/br. 2020.1290

D Russo, F Merolla, S Varricchio… - Biomedical …, 2018 - spandidos-publications.com
Oral and oropharyngeal cancers represent the two most common malignancies of the head
and neck region. The major risk factors for these cancers include alcohol consumption …

Salivary DNA methylation panel to diagnose HPV-positive and HPV-negative head and neck cancers

Y Lim, Y Wan, D Vagenas, DA Ovchinnikov, CFL Perry… - BMC cancer, 2016 - Springer
Background Head and neck squamous cell carcinoma (HNSCC) is a heterogeneous group
of tumours with a typical 5 year survival rate of< 40%. DNA methylation in tumour …

Recent trends of saliva omics biomarkers for the diagnosis and treatment of oral cancer

I Chattopadhyay, M Panda - Journal of oral biosciences, 2019 - Elsevier
Background Recent advances in surgery, radiotherapy, and chemotherapy have no
significant effect on oral cancer survival rates due to late diagnosis, poor tumor response to …

Salivary miRNA-21 expression as a potential non-invasive diagnostic biomarker in breast cancer

M Koopaie, F Abedinejad, S Manifar, R Mousavi… - Gene Reports, 2021 - Elsevier
Introduction Breast cancer (BC) is the most common neoplasm and the most important
cause of mortality in women worldwide. microRNAs (miRNAs) are single-stranded RNA …

An update on oral cavity cancer: epidemiological trends, prevention strategies and novel approaches in diagnosis and prognosis

M Gormley, E Gray, C Richards… - … Dental Health Journal, 2022 - orca.cardiff.ac.uk
In the UK, the incidence of oral cavity cancer continues to rise, with an increase of around
60% over the past 10 years. Many patients still present with advanced disease, often …

Contribution of genomics to the surgical management and study of oral cancer

Z Saidak, C Lailler, S Testelin, B Chauffert… - Annals of Surgical …, 2021 - Springer
Background Oral squamous cell carcinoma (OSCC) is the most frequent type of tumor
arising from the oral cavity. Surgery is the cornerstone of the treatment of these cancers …