[HTML][HTML] Discovery and resupply of pharmacologically active plant-derived natural products: A review

AG Atanasov, B Waltenberger… - Biotechnology …, 2015 - Elsevier
Medicinal plants have historically proven their value as a source of molecules with
therapeutic potential, and nowadays still represent an important pool for the identification of …

Current approaches and challenges for the metabolite profiling of complex natural extracts

JL Wolfender, G Marti, A Thomas, S Bertrand - Journal of Chromatography …, 2015 - Elsevier
Metabolite profiling is critical in many aspects of the life sciences, particularly natural product
research. Obtaining precise information on the chemical composition of complex natural …

Accelerating metabolite identification in natural product research: toward an ideal combination of liquid chromatography–high-resolution tandem mass spectrometry …

JL Wolfender, JM Nuzillard, JJJ Van Der Hooft… - Analytical …, 2018 - ACS Publications
Natural product research aims to characterize specialized metabolites from various living
organisms and assess their biological properties from either a chemical ecology or drug …

Metabolite induction via microorganism co-culture: a potential way to enhance chemical diversity for drug discovery

S Bertrand, N Bohni, S Schnee, O Schumpp… - Biotechnology …, 2014 - Elsevier
Microorganisms have a long track record as important sources of novel bioactive natural
products, particularly in the field of drug discovery. While microbes have been shown to …

Green (cell) factories for advanced production of plant secondary metabolites

AS Marchev, ZP Yordanova… - Critical reviews in …, 2020 - Taylor & Francis
For centuries plants have been intensively utilized as reliable sources of food, flavoring,
agrochemical and pharmaceutical ingredients. However, plant natural habitats are being …

Universal quantitative NMR analysis of complex natural samples

C Simmler, JG Napolitano, JB McAlpine… - Current opinion in …, 2014 - Elsevier
Highlights•qNMR is a powerful analytical tool for structure and purity determination.•qNMR is
suitable for the quality control of complex natural samples.•qNMR and MS-hyphenated …

Review on metabolomics for food authentication

E Cubero-Leon, R Peñalver, A Maquet - Food Research International, 2014 - Elsevier
European and global food policies require that food put on the market is authentic, which
means that the label declaration matches the composition and provenance of the food item …

Plant metabolomics: a new strategy and tool for quality evaluation of Chinese medicinal materials

Q Xiao, X Mu, J Liu, B Li, H Liu, B Zhang, P Xiao - Chinese Medicine, 2022 - Springer
The present quality control method of Chinese medicinal materials (CMM) has obvious
deficiency, which cannot be compatible with the multi-target and multi-component …

NuBBEDB: an updated database to uncover chemical and biological information from Brazilian biodiversity

AC Pilon, M Valli, AC Dametto, MEF Pinto, RT Freire… - Scientific Reports, 2017 - nature.com
The intrinsic value of biodiversity extends beyond species diversity, genetic heritage,
ecosystem variability and ecological services, such as climate regulation, water quality …

[HTML][HTML] Future directions for the discovery of natural product-derived immunomodulating drugs: an IUPHAR positional review

CL Wainwright, MM Teixeira, DL Adelson… - Pharmacological …, 2022 - Elsevier
Drug discovery from natural sources is going through a renaissance, having spent many
decades in the shadow of synthetic molecule drug discovery, despite the fact that natural …