Molecular mechanisms of COVID-19-induced pulmonary fibrosis and epithelial-mesenchymal transition

P Pi, Z Zeng, L Zeng, B Han, X Bai, S Xu - Frontiers in Pharmacology, 2023 - frontiersin.org
As the outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) first broke out in Hubei Province, China, at the end of 2019. It has brought …

[HTML][HTML] SARS-CoV-2 S and N protein peptides drive invasion abilities of colon cancer cells through TGF-β1 regulation

WM Ciszewski, LA Wozniak, K Sobierajska - Biochimica et Biophysica Acta …, 2023 - Elsevier
The COVID-19 pandemic led to the delay of colorectal cancer (CRC) diagnosis, which
causes CRC to be treated at more advanced, often metastatic stages. Unfortunately, there is …

Integrating AI/ML models for patient stratification leveraging omics dataset and clinical biomarkers from COVID-19 patients: A promising approach to personalized …

B Bello, YN Bundey, R Bhave, M Khotimchenko… - International Journal of …, 2023 - mdpi.com
The COVID-19 pandemic has presented an unprecedented challenge to the healthcare
system. Identifying the genomics and clinical biomarkers for effective patient stratification …

Perspectives on Post-COVID-19 Pulmonary Fibrosis Treatment

E Cojocaru, T Cojocaru, GM Pînzariu, I Vasiliu… - Journal of Personalized …, 2023 - mdpi.com
Pulmonary fibrosis, a critical outcome of chronic inflammatory diseases, has gained
prominence in the context of post-coronavirus (post-COVID-19) complications. This review …

Exosomal miR-17-5p, miR-146a-3p, and miR-223-3p Correlate with Radiologic Sequelae in Survivors of COVID-19-Related Acute Respiratory Distress Syndrome

R Curcio, G Poli, C Fabi, C Sugoni, MB Pasticci… - International Journal of …, 2023 - mdpi.com
We investigated the association between circulating microRNAs (miRNAs) potentially
involved in the lung inflammatory process and fibrosis development among COVID-19 …

Persistent Vascular Complications in Long COVID: The Role of ACE2 Deactivation, Microclots, and Uniform Fibrosis

CM Sideratou, C Papaneophytou - Infectious Disease Reports, 2024 - mdpi.com
Angiotensin-converting enzyme 2 (ACE2), a key regulator in vasoregulation and the renin–
angiotensin system, is hypothesized to be downregulated in patients with COVID-19 …

Nonspecific interstitial pneumonia pattern is a frequent finding in patients with post-acute COVID-19 syndrome treated with bilateral orthotopic lung transplantation …

S Mortazavi, M de Peralta-Venturina, AM Marchevsky - Human Pathology, 2023 - Elsevier
Patients with post-acute COVID-19 (PA-COVID) syndrome or long COVID-19 syndrome
develop persistent symptoms and complications that last beyond 4 weeks of the initial …

Pulmonary fibrosis as a sequela of COVID-19 infection: What do we know?

SNV Putri - Eurasian Journal of Pulmonology, 2023 - eurasianjpulmonol.com
Abstract Coronavirus Disease 2019 (COVID-19), a highly infectious disease caused by
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), has emerged as a …