The delivery of nucleic acids with transient activity for genetic engineering is a promising
methodology with potential applications in the treatment of diseases ranging from cancer …

RNA interference with the ability to specifically silence target genes has shown great
potential to treat various diseases. The primary challenge for RNA interference is to …

Self‐assembly of peptide‐based building units into supramolecular nanostructures creates
an important class of biomaterials with robust mechanical properties and improved …

Cell penetrating peptides (CPPs), and protein transduction domains (PTDs) of viruses and
other natural proteins serve as a template for the development of efficient peptide based …

The bola-amphiphilic arginine-capped peptide RFL4RF self-assembles into nanotubes in
aqueous solution. The nanostructure and rheology are probed by in situ simultaneous …

Transfecting nucleic acids into cells is an essential procedure in biological research usually
performed using nonviral transfection reagents. Unfortunately, most transfection reagents …

Bolaamphiphile, which is a class of amphiphilic molecules, has a unique structure of two
hydrophilic head groups at the ends of the hydrophobic center. Peptidic bolaamphiphiles …

Bolaamphiphiles (BAs) are structurally segmented molecules with rich assembly
characteristics and diverse physical properties. Interest in BAs as standalone active agents …

RNA-based therapeutics have garnered tremendous attention due to their potential to
revolutionize protein replacement therapies, immunotherapy, and treatment of genetic …

Obesity is a major risk factor for diabetes, heart disease and other health problems. Adipose
tissue plays a central role in the development of obesity and obesity-associated diseases …