The aldol reaction is one of the most important methods for the stereoselective construction
of polyketide natural products, not only for nature but also for synthetic chemistry. The …

Covering: 2006. Previous review: Nat. Prod. Rep., 2007, 24, 31 This review covers the
literature published in 2006 for marine natural products, with 758 citations (534 for the …

GIAO NMR shift calculation has been applied to the challenging task of reliably assigning
stereochemistry with quantifiable confidence when only one set of experimental data are …

The selective formation of bondings between molecules is one of the major challenges in
organic chemistry, and the so-called aldol reaction is one of the most important for this …

Leiodermatolide is an antimitotic macrolide isolated from the marine sponge Leiodermatium
sp. whose potentially novel tubulin‐targeting mechanism of action makes it an exciting lead …

Die Aldolreaktion gehört zu den wichtigsten Methoden der organischen Synthesechemie für
den stereoselektiven Aufbau von polyketiden Naturstoffen. Dabei bedient sich die Natur …

We present a protocol that combines the support vector machine (SVM) model with accurate
13C chemical shift calculations at the xOPBE/6-311+ G (2d, p) level of theory, denoted as …

Comprehensive Summary A total synthesis of 17‐membered macrocyclolipopeptide
dysoxylactam A, a potent agent reversing P‐glycoprotein (P‐gp)‐mediated multidrug …

Titanium enolate-based aldol additions have a tremendous synthetic potential. Titanium
reagents are readily available, inexpensive, nontoxic and easy to handle. 1, 2 First aldol …

The first total synthesis of myxobacteria metabolite icumazole A (1) is reported. Key steps in
the route include an organocatalyzed asymmetric self-aldol reaction followed by an acetate …