Neuroimmune axes of the blood–brain barriers and blood–brain interfaces: bases for physiological regulation, disease states, and pharmacological interventions

MA Erickson, WA Banks - Pharmacological reviews, 2018 - ASPET
Central nervous system (CNS) barriers predominantly mediate the immune-privileged status
of the brain, and are also important regulators of neuroimmune communication. It is …

Progressive multifocal leukoencephalopathy: current insights

M Kartau, JOT Sipilä, E Auvinen… - Degenerative …, 2019 - Taylor & Francis
Cases of PML should be evaluated according to predisposing factors, as these subgroups
differ by incidence rate, clinical course, and prognosis. The three most significant groups at …

Magnetic resonance imaging pattern in natalizumab‐associated progressive multifocal leukoencephalopathy

TA Yousry, D Pelletier, D Cadavid, A Gass… - Annals of …, 2012 - Wiley Online Library
Objective: Natalizumab is an effective treatment for patients with multiple sclerosis (MS) that
is associated with a risk of progressive multifocal leukoencephalopathy (PML) …

Progressive multifocal leukoencephalopathy: a review of the neuroimaging features and differential diagnosis

MA Sahraian, EW Radue, A Eshaghi… - European Journal of …, 2012 - Wiley Online Library
Progressive multifocal leukoencephalopathy (PML) is an uncommon and often fatal
demyelinating disease of human central nervous system, which is caused by reactivation of …

Progressive multifocal leukoencephalopathy: why gray and white matter

S Gheuens, C Wüthrich… - Annual Review of …, 2013 - annualreviews.org
Since it was first described in 1958, progressive multifocal leukoencephalopathy (PML), a
demyelinating disease of the brain caused by the polyomavirus JC (JCV), has evolved …

[HTML][HTML] The neurological sequelae of pandemics and epidemics

F Valerio, DP Whitehouse, DK Menon… - Journal of …, 2021 - Springer
Neurological manifestations in pandemics frequently cause short and long-term
consequences which are frequently overlooked. Despite advances in the treatment of …

[HTML][HTML] Middle cerebellar peduncles: Magnetic resonance imaging and pathophysiologic correlate

H Morales, T Tomsick - World journal of radiology, 2015 - ncbi.nlm.nih.gov
We describe common and less common diseases that can cause magnetic resonance
signal abnormalities of middle cerebellar peduncles (MCP), offering a systematic approach …

Punctate pattern: a promising imaging marker for the diagnosis of natalizumab-associated PML

J Hodel, C Darchis, O Outteryck, S Verclytte… - Neurology, 2016 - AAN Enterprises
Objective: To evaluate the usefulness of the punctate pattern (PP) for the diagnosis and
follow-up of patients with progressive multifocal leukoencephalopathy (PML). Methods: A …

[HTML][HTML] Diagnosis and treatment of progressive multifocal leukoencephalopathy associated with multiple sclerosis therapies

EML Williamson, JR Berger - Neurotherapeutics, 2017 - Elsevier
Progressive multifocal leukoencephalopathy (PML) is a rare, but serious, complication
encountered in patients treated with a select number of disease-modifying therapies (DMTs) …

JC virus spread is potentiated by glial replication and demyelination-linked glial proliferation

C Li, NPT Huynh, SJ Schanz, MS Windrem… - Brain, 2024 - academic.oup.com
Progressive multifocal leukoencephalopathy is a demyelinating infection of the
immunosuppressed brain, mediated by the gliotropic polyomavirus JCV. JCV replicates in …