Combinatorial therapeutic enzymes to combat multidrug resistance in bacteria

A Upadhyay, D Pal, A Kumar - Life Sciences, 2024 - Elsevier
Aims Antibiotic resistance including multidrug resistance (MDR) is a negative symbol to the
human health system because it loses the capability to treat infections. Unfortunately, the …

Interrogating Salmonella Typhi biofilm formation and dynamics to understand antimicrobial resistance

A Upadhyay, D Pal, A Kumar - Life Sciences, 2024 - Elsevier
Abstract Aims Salmonella Typhi biofilm-mediated infections are globally rising. Due to the
emergence of drug resistance antibiotics did not show effective results against S. Typhi …

Cellulase exhibited a therapeutic potential to inhibit Salmonella enterica serovar Typhi biofilm by targeting multiple regulatory proteins of biofilm

A Upadhyay, D Pal, A Kumar - Microbial Pathogenesis, 2024 - Elsevier
Biofilm-mediated Salmonella enterica serovar Typhi (Salmonella Ser. Typhi) infections are a
growing global health issue due to the formation of antibiotic resistance. The study aimed to …

Antimicrobial therapeutic protein extraction from fruit waste and recent trends in their utilization against infections

A Upadhyay, D Pal, PK Gupta, A Kumar - Bioprocess and Biosystems …, 2024 - Springer
Fruits are a very good source of various nutrients that can boost overall human health. In
these days, the recovery of therapeutic compounds from different fruit wastes is trending in …

Biofilm Battle: New transformative tactics to tackle the bacterial biofilm infections

A Upadhyay, N Jaiswal, A Kuamr - Microbial Pathogenesis, 2025 - Elsevier
Bacterial biofilm infections are the root cause of persistent infections and the prevalence of
resistance to specific or multiple antibiotics. Biofilms have unique features that provide a …

Molecular drilling to combat salmonella typhi biofilm using L-Asparaginase via multiple targeting process

A Upadhyay, D Pal, A Kumar - Expert Opinion on Therapeutic …, 2024 - Taylor & Francis
ABSTRACT Objectives Salmonella Typhi biofilm condition is showing as a major public
health problem due to the development of antibiotic resistance and less available druggable …

Development of the dynamic approach for detection of Salmonella Typhi biofilm via optimizations of interaction with safranin dye

A Upadhyay, D Pal, A Kumar - Biologia, 2024 - Springer
Salmonella Typhi infection is showing as a negative alarm for human health due to the
occurrence of life-threatening typhoid fever and the emergence of antibiotic resistance. The …

History of the human viral infection and their clinical manifestation

Y Karkhur, A Upadhyay, A Kumar - Cytokine Response Against Major …, 2025 - Elsevier
In the contemporary era, humanity grapples with chronic viral infections, exemplified by
diseases like COVID-19 and HIV. Viruses, as agents of infection, have a long history dating …