Return to sports after ACL injury 5 years from now: 10 things we must do

A Gokeler, A Grassi, R Hoogeslag… - Journal of experimental …, 2022 - Springer
Background The outcome after ACL reconstruction (ACLR) is in general disappointing with
unacceptable number of athletes that do not return to pre-injury level of sports, high re-injury …

Bone fragility and osteoporosis in children and young adults

MM Formosa, MA Christou, O Mäkitie - Journal of Endocrinological …, 2024 - Springer
Osteoporosis is a metabolic bone disorder which increases fragility fracture risk. Elderly
individuals, especially postmenopausal women, are particularly susceptible to osteoporosis …

Functional validation of osteoporosis genetic findings using small fish models

E Kague, D Karasik - Genes, 2022 - mdpi.com
The advancement of human genomics has revolutionized our understanding of the genetic
architecture of many skeletal diseases, including osteoporosis. However, interpreting results …

Bone Trans-omics: Integrating Omics to Unveil Mechanistic Molecular Networks Regulating Bone Biology and Disease

BH Mullin, ABP Ribet, NJ Pavlos - Current Osteoporosis Reports, 2023 - Springer
Abstract Purpose of Review Recent advancements in “omics” technologies and
bioinformatics have afforded researchers new tools to study bone biology in an unbiased …

Discovery of potential biomarkers for osteoporosis diagnosis by individual omics and multi-omics technologies

J Yang, J Wu - Expert Review of Molecular Diagnostics, 2023 - Taylor & Francis
Introduction Global aging has made osteoporosis an increasingly serious public health
problem. Osteoporotic fractures seriously affect the quality of life of patients and increase …

Copy Number Variation and Osteoporosis

N Lovšin - Current osteoporosis reports, 2023 - Springer
Abstract Purpose of Review The purpose of this review is to summarize recent findings on
copy number variations and susceptibility to osteoporosis. Recent Findings Osteoporosis is …

The genetic overlap between osteoporosis and craniosynostosis

E Kague, C Medina-Gomez, SA Boyadjiev… - Frontiers in …, 2022 - frontiersin.org
Osteoporosis is the most prevalent bone condition in the ageing population. This systemic
disease is characterized by microarchitectural deterioration of bone, leading to increased …

Zebrafish as a Model for Osteoporosis: Functional Validations of Genome-Wide Association Studies

I Ben-Zvi, D Karasik, CL Ackert-Bicknell - Current Osteoporosis Reports, 2023 - Springer
Purpose of Review GWAS, as a largely correlational analysis, requires in vitro or in vivo
validation. Zebrafish (Danio rerio) have many advantages for studying the genetics of …

Identification of osteoporosis genes using family studies

M Schembri, MM Formosa - Frontiers in Endocrinology, 2024 - frontiersin.org
Osteoporosis is a multifactorial bone disease characterised by reduced bone mass and
increased fracture risk. Family studies have made significant contribution in unravelling the …

A Review of Histological Techniques for Differentiating Human Bone from Animal Bone

E Stan, CO Muresan, E Daescu, R Dumache… - Methods and …, 2024 - mdpi.com
The first step in anthropological study is the positive identification of human remains, which
can be a challenging undertaking when bones are broken. When bone pieces from different …