Stool and blood biomarkers for colorectal cancer management: an update on screening and disease monitoring

A Mannucci, A Goel - Molecular Cancer, 2024 - Springer
Background Biomarkers have revolutionized the management of colorectal cancer (CRC),
facilitating early detection, prevention, personalized treatment, and minimal residual disease …

[HTML][HTML] Liquid biopsy in the clinical management of cancers

HY Ho, KS Chung, CM Kan, SC Wong - International Journal of Molecular …, 2024 - mdpi.com
Liquid biopsy, a noninvasive diagnosis that examines circulating tumor components in body
fluids, is increasingly used in cancer management. An overview of relevant literature …

Evaluation of long-term benefits and cost-effectiveness of nation-wide colorectal cancer screening strategies in China in 2020–2060: a modelling analysis

B Lu, J Luo, Y Yan, Y Zhang, C Luo, N Li… - The Lancet Regional …, 2024 - thelancet.com
Background Evidence on the long-term benefits and cost-effectiveness of colorectal cancer
(CRC) screening strategies in China remains limited. This modelling study aims to address …

Cost-Effectiveness of Noninvasive Colorectal Cancer Screening in Community Clinics

PN de Lima, L Matrajt, G Coronado… - JAMA Network …, 2025 - jamanetwork.com
Importance Several noninvasive tests for colorectal cancer screening are available, but their
effectiveness in settings with low adherence to screening and follow-up colonoscopy is not …

[HTML][HTML] Diagnostic Accuracy of a Blood-Based Biomarker Panel for Colorectal Cancer Detection: A Pilot Study

EV Caraballo, H Centeno-Girona… - Cancers, 2024 - mdpi.com
Background: Colorectal cancer (CRC) is a leading cause of death worldwide. Despite its
preventability through screening, compliance still needs to improve due to the invasiveness …

Estimated impact and value of blood-based colorectal cancer screening at varied adherence compared with stool-based screening

JB Kisiel, AM Fendrick, DW Ebner… - Journal of Medical …, 2024 - Taylor & Francis
Objective This analysis estimated the outcomes of triennial blood-based colorectal cancer
(CRC) screening at various adherence, including perfect adherence, compared with …

Population health outcomes of blood-based screening for colorectal cancer in comparison to current screening modalities: insights from a discrete-event simulation …

SP Forbes, E Yay Donderici, N Zhang… - Journal of Medical …, 2024 - Taylor & Francis
Aim Insufficient adherence to colorectal cancer (CRC) screening impedes individual and
population health benefits, with about one-third of individuals non-adherent to available …

Can molecular cancer signals circulating in blood help us prevent cancer-related deaths?

U Ladabaum, JA Dominitz, D Lieberman, RE Schoen - The Lancet, 2025 - thelancet.com
Breakthroughs in laboratory and data science are increasing interest in blood tests to screen
for cancer, with colorectal cancer screening at the forefront of this interest. 1 These emerging …

How Good Is Good Enough? What Should Be the Target for CRC Screening?

D Lieberman, E Dekker - Digestive Diseases and Sciences, 2024 - Springer
Colorectal Cancer (CRC) screening of average-risk individuals has been shown to reduce
CRC mortality and incidence. Incidence is reduced by detection and removal of cancer …

Colorectal Cancer Screening: Increasing the Options

TJ O'Leary - The Journal of Molecular Diagnostics, 2024 - jmdjournal.org
This year, approximately 150,000 individuals in the United States will be diagnosed with
colorectal cancer (CRC), and> 50,000 will die from the disease (https://seer. cancer …