Multiciliated cells are epithelial cells that are in contact with bodily fluids and are required for
the proper function of major organs including the brain, the respiratory system and the …

In this review, a companion piece to our recent examination of choroid plexus (CP), the
organ that secretes the cerebrospinal fluid (CSF), we focus on recent information in the …

Primary ciliary dyskinesia (PCD) is a genetically heterogeneous recessive disorder of motile
cilia that leads to oto-sino-pulmonary diseases and organ laterality defects in approximately …

Hydrocephalus is a common but complex condition caused by physical or functional
obstruction of CSF flow that leads to progressive ventricular dilatation. Though …

Hydrocephalus is classically considered as a failure of cerebrospinal fluid (CSF)
homeostasis that results in the active expansion of the cerebral ventricles. Infants with …

Congenital hydrocephalus is a relatively common and debilitating birth defect with several
known physiological causes. Dysfunction of motile cilia on the ependymal cells that line the …

The vertebrate body plan is characterized by the presence of a segmented spine along its
main axis. Here, we examine the current understanding of how the axial tissues that are …

Primary ciliary dyskinesia (PCD) is a rare autosomal recessive disease, caused by specific
primary structural and/or functional abnormalities of the motile cilia, in contrast with the …

Pediatric hydrocephalus is characterized by an abnormal accumulation of cerebrospinal
fluid (CSF) and is one of the most common congenital brain abnormalities. However, little is …

Objective To report a neuroradiologic phenotype associated with reduced generation of
multiple motile cilia (RGMC) and mutations in the multicilin gene. We hypothesize that the …