Creatine is one of the most popular nutritional ergogenic aids for athletes. Studies have
consistently shown that creatine supplementation increases intramuscular creatine …

Although creatine has been mostly studied as an ergogenic aid for exercise, training, and
sport, several health and potential therapeutic benefits have been reported. This is because …

Creatine is physiologically provided equally by diet and by endogenous synthesis from
arginine and glycine with successive involvements of arginine glycine amidinotransferase …

Creatine kinase catalyses the reversible transphosphorylation of creatine by ATP. In the cell,
creatine kinase isoenzymes are specifically localized at strategic sites of ATP consumption …

Athletes, body builders, and military personnel use dietary creatine as an ergogenic aid to
boost physical performance in sports involving short bursts of high-intensity muscle activity …

BACKGROUND: Intellectual disability ('developmental delay'at age< 5years) affects 2.5% of
population worldwide. Recommendations to investigate genetic causes of intellectual …

J. Neurochem.(2010) 115, 297–313. Abstract Apart of its well known function of 'energetic
buffer'through the creatine/phosphocreatine/creatine kinase system allowing the …

Creatine (Cr) is an important organic compound acting as intracellular high-energy
phosphate shuttle and in energy storage. While located in most cells where it plays its main …

Background Creatine transporter deficiency is a monogenic cause of X-linked intellectual
disability. Since its first description in 2001 several case reports have been published but an …

We collected data on 48 patients from 38 families with guanidinoacetate methyltransferase
(GAMT) deficiency. Global developmental delay/intellectual disability (DD/ID) with …