Development of nanotechnology-mediated precision radiotherapy for anti-metastasis and radioprotection

Y Pan, W Tang, W Fan, J Zhang, X Chen - Chemical Society Reviews, 2022 - pubs.rsc.org
Radiotherapy (RT), including external beam RT and internal radiation therapy, uses high-
energy ionizing radiation to kill tumor cells. However, ionizing radiation inevitably damages …

Radiation-induced lung injury (RILI)

L Giuranno, J Ient, D De Ruysscher, MA Vooijs - Frontiers in oncology, 2019 - frontiersin.org
Radiation pneumonitis (RP) and radiation fibrosis (RF) are two dose-limiting toxicities of
radiotherapy (RT), especially for lung, and esophageal cancer. It occurs in 5–20% of …

[HTML][HTML] Glial cells and their function in the adult brain: a journey through the history of their ablation

S Jäkel, L Dimou - Frontiers in cellular neuroscience, 2017 - frontiersin.org
Glial cells, consisting of microglia, astrocytes and oligodendrocyte lineage cells as their
major components, constitute a large fraction of the mammalian brain. Originally considered …

Cerium oxide nanoparticle: a remarkably versatile rare earth nanomaterial for biological applications

C Xu, X Qu - NPG Asia materials, 2014 - nature.com
Cerium oxide nanoparticles (CeONPs) have received much attention because of their
excellent catalytic activities, which are derived from quick and expedient mutation of the …

Bacterial flagellin—a potent immunomodulatory agent

IA Hajam, PA Dar, I Shahnawaz, JC Jaume… - … & molecular medicine, 2017 - nature.com
Flagellin is a subunit protein of the flagellum, a whip-like appendage that enables bacterial
motility. Traditionally, flagellin was viewed as a virulence factor that contributes to the …

Strategies for optimizing the response of cancer and normal tissues to radiation

EJ Moding, MB Kastan, DG Kirsch - Nature reviews Drug discovery, 2013 - nature.com
Approximately 50% of all patients with cancer receive radiation therapy at some point during
the course of their treatment, and the majority of these patients are treated with curative …

Radiation induces proinflammatory dysbiosis: transmission of inflammatory susceptibility by host cytokine induction

S Gerassy-Vainberg, A Blatt, Y Danin-Poleg… - Gut, 2018 - gut.bmj.com
Objective Radiation proctitis (RP) is a complication of pelvic radiotherapy which affects both
the host and microbiota. Herein we assessed the radiation effect on microbiota and its …

Potential role of natural antioxidant products in oncological diseases

P Marino, G Pepe, MG Basilicata, V Vestuto… - Antioxidants, 2023 - mdpi.com
Nutrition has a significant effect and a crucial role in disease prevention. Low consumption
of fruit and vegetables and a sedentary lifestyle are closely related with the onset and …

How do chemotherapeutic agents damage the ovary?

S Morgan, RA Anderson, C Gourley… - Human reproduction …, 2012 - academic.oup.com
BACKGROUND Chemotherapy treatment in premenopausal women is associated with an
increased risk of premature ovarian failure (POF) but the exact mechanism through which …

Radiation‐induced normal tissue damage: oxidative stress and epigenetic mechanisms

J Wei, B Wang, H Wang, L Meng… - Oxidative medicine …, 2019 - Wiley Online Library
Radiotherapy (RT) is currently one of the leading treatments for various cancers; however, it
may cause damage to healthy tissue, with both short‐term and long‐term side effects …