The prognostic value of tumor-associated macrophages detected by immunostaining in diffuse large B cell lymphoma: A meta-analysis

M Lin, S Ma, L Sun, Z Qin - Frontiers in Oncology, 2023 - frontiersin.org
Background The prognostic implication of tumor-associated macrophages (TAMs) in the
microenvironment of diffuse large B cell lymphoma (DLBCL) remains controversial. Methods …

Inhibition of LXR controls the polarization of human inflammatory macrophages through upregulation of MAFB

AG de la Aleja, C Herrero, M Torres-Torresano… - Cellular and Molecular …, 2023 - Springer
Monocyte-derived macrophages contribute to pathogenesis in inflammatory diseases and
their effector functions greatly depend on the prevailing extracellular milieu. Whereas M-CSF …

[HTML][HTML] Insights into the glioblastoma tumor microenvironment: current and emerging therapeutic approaches

DK Tripathy, LP Panda, S Biswal… - Frontiers in …, 2024 - frontiersin.org
Glioblastoma (GB) is an intrusive and recurrent primary brain tumor with low survivability.
The heterogeneity of the tumor microenvironment plays a crucial role in the stemness and …

Dissecting the tumour immune microenvironment in merkel cell carcinoma based on a machine learning framework

S Cheng, S Li, P Yang, R Wang, P Zhou… - Artificial Cells …, 2023 - Taylor & Francis
Merkel cell carcinoma (MCC) is a primary cutaneous neoplasm of neuroendocrine
carcinoma of the skin, which is characterized by molecular heterogeneity with diverse …

Exploring the role of macrophages in the progression from atypical hyperplasia to endometrial carcinoma through single-cell transcriptomics and bulk transcriptomics …

X Song, R Na, N Peng, W Cao, Y Ke - Frontiers in endocrinology, 2023 - frontiersin.org
Introduction In this study, we aimed to identify key genes in endometrial cancer by
conducting single-cell analysis of macrophages. Methods We sourced clinical data from the …

Macrophage-Based Therapeutic Strategies in Hematologic Malignancies

S Khalili, F Zeinali, A Moghadam Fard, SR Taha… - Cancers, 2023 - mdpi.com
Simple Summary Tumor-associated macrophages (TAMs) are the most prevalent
immunosuppressive myeloid cells in the tumor microenvironment, playing significant …

Anti-lung cancer synergy of low-dose doxorubicin and PD-L1 blocker co-delivered via mild photothermia-responsive black phosphorus

HZ Xu, FX Chen, K Li, Q Zhang, N Han, T Li… - Drug Delivery and …, 2024 - Springer
We have previously identified a latent interaction mechanism between non-small cell lung
cancer cells (NSCLCC) and their associated macrophages (TAM) mediated by mutual …

A decision-tree approach to stratify DLBCL risk based on stromal and immune microenvironment determinants

GM Zaccaria, MC Vegliante, G Mezzolla… - …, 2023 - journals.lww.com
In diffuse large B-cell lymphoma (DLBCL), the heterogeneity of response to standard first-
line therapy 1 largely relies on the tremendous biological complexity of the disease, claiming …

[PDF][PDF] Macrophage-Based Therapeutic Strategies in Hematologic Malignancies. Cancers 2023, 15, 3722

S Khalili, F Zeinali, A Moghadam Fard, SR Taha… - 2023 - researchgate.net
Macrophages are types of immune cells, with ambivalent functions in tumor growth, which
depend on the specific environment in which they reside. Tumor-associated macrophages …