Notch signaling is an evolutionarily highly conserved signaling mechanism, but in contrast to
signaling pathways such as Wnt, Sonic Hedgehog, and BMP/TGF-β, Notch signaling occurs …

Pluripotent stem cells show a remarkable ability to self-organize and differentiate in vitro in
three-dimensional aggregates, known as organoids or organ spheroids, and to recapitulate …

Although mechanisms of embryonic development are similar between mice and humans,
the time scale is generally slower in humans. To investigate these interspecies differences in …

We study the emergent behaviors of a population of swarming coupled oscillators, dubbed
swarmalators. Previous work considered the simplest, idealized case: identical …

The segmental organization of the vertebral column is established early in embryogenesis,
when pairs of somites are rhythmically produced by the presomitic mesoderm (PSM). The …

The goal of this review article is to assess how relevant is the concept of dissipative structure
for understanding the dynamical bases of non-equilibrium self-organization in biological …

Segmentation is a fundamental feature of the vertebrate body plan. This metameric
organization is first implemented by somitogenesis in the early embryo, when paired …

Self-organization is pervasive in development, from symmetry breaking in the early embryo
to tissue patterning and morphogenesis. For a few model systems, the underlying molecular …

We study the collective behavior of swarmalators, generalizations of phase oscillators that
both sync and swarm, confined to move on a one-dimensional (1D) ring. This simple model …

The field of single-cell biology has morphed from a philosophical digression at its inception,
to a playground for quantitative biologists, to a major area of biomedical research. The last …