[HTML][HTML] Nanosuspensions technology as a master key for nature products drug delivery and in vivo fate

Y Ma, Z Cong, P Gao, Y Wang - European Journal of Pharmaceutical …, 2023 - Elsevier
The drug nanosuspensions is a universal formulation approach for improved drug delivery
of hydrophobic drugs and one the most promising approaches for increasing the …

Long-acting parenteral drug delivery systems for the treatment of chronic diseases

AB Jindal, AR Bhide, S Salave, D Rana… - Advanced Drug Delivery …, 2023 - Elsevier
The management of chronic conditions often requires patients to take daily medication for an
extended duration. However, the need for daily dosing can lead to nonadherence to the …

Memantine‐loaded PEGylated biodegradable nanoparticles for the treatment of glaucoma

E Sánchez‐López, MA Egea, BM Davis, L Guo… - Small, 2018 - Wiley Online Library
Glaucoma is a multifactorial neurodegenerative disease associated with retinal ganglion
cells (RGC) loss. Increasing reports of similarities in glaucoma and other neurodegenerative …

Long-acting injectables: current perspectives and future promise

K Chaudhary, MM Patel… - Critical Reviews™ in …, 2019 - dl.begellhouse.com
The parenteral route of administration is preferred over the oral route for treatment of many
chronic and life-threatening diseases due to better patient compliance. Long-acting …

Nanotechnology as a platform for the development of injectable parenteral formulations: a comprehensive review of the know-hows and state of the art

MA Shetab Boushehri, D Dietrich, A Lamprecht - Pharmaceutics, 2020 - mdpi.com
Within recent decades, the development of nanotechnology has made a significant
contribution to the progress of various fields of study, including the domains of medical and …

A novel multi-target strategy for Alzheimer's disease treatment via sublingual route: donepezil/memantine/curcumin-loaded nanofibers

F Topal, B Ertas, E Guler, F Gurbuz, GS Ozcan… - Biomaterials …, 2022 - Elsevier
Drug delivery systems that not only show efficacy through multiple therapeutic pathways but
also facilitate patient drug use and exhibit a high bioavailability profile represent a promising …

Delivery of ionizable hydrophilic drugs based on pharmaceutical formulation of ion pairs and ionic liquids

A Gamboa, N Schüßler, E Soto-Bustamante… - European Journal of …, 2020 - Elsevier
New therapeutics such as antisense oligonucleotides, small interfering RNA and peptide-
drug conjugates are taking great relevance in the pharmaceutical industry due to their …

The first nano-cocrystal formulation of marine drug cytarabine with uracil based on cocrystal nanonization strategy for long-acting injection exhibiting enhanced …

YM Yu, FZ Bu, SS Meng, CW Yan, ZY Wu… - International Journal of …, 2023 - Elsevier
To emphasize the superiority of uracil (UR) in ameliorating biopharmaceutical
characteristics of marine antitumor medicine cytarabine (ARA), thus gaining some innovative …

In vitro and in vivo evaluation of multi-target-directed Rivastigmine/Memantine/Gingko biloba-loaded nanofibers against Alzheimer's disease

S Veysanoglu, B Ertas, E Guler, F Topal… - Journal of Drug Delivery …, 2023 - Elsevier
The highly complex pathophysiology of Alzheimer's disease (AD) and the low bioavailability
of the currently used drugs make it necessary to offer versatile treatment options. In this …

Study of interacting mechanism of amino acid and Alzheimer's drug using vibrational techniques and computational method

J Saikia, B Borah, TG Devi - Journal of Molecular Structure, 2021 - Elsevier
The present work is undertaken to investigate the molecular interaction between Memantine
(Alzheimer's drug) and DL-Alanine (amino acid) using DFT and vibrational spectroscopic …