Sialic acids are a diverse family of monosaccharides widely expressed on all cell surfaces of
vertebrates and so‐called “higher” invertebrates, and on certain bacteria that interact with …

The field of red cell biology is undergoing a quiet revolution. Long assumed to be inert
oxygen carriers, RBCs are emerging as important modulators of the innate immune …

Human red blood cells (RBC) are highly differentiated cells that have lost all organelles and
most intracellular machineries during their maturation process. RBC are fundamental for the …

While hemostasis is the physiological process that prevents blood loss after vessel injury,
thrombosis is often portrayed as a pathologic event involving blood coagulation and platelet …

The field of molecular evolution has experienced explosive growth in recent years due to the
rapid accumulation of genetic sequence data, continuous improvements to computer …

Malaria is a major killer of children worldwide and the strongest known force for evolutionary
selection in the recent history of the human genome. The past decade has seen growing …

Identifying genomic regions that have been targets of natural selection remains one of the
most important and challenging areas of research in genetics. To this end, we report an …

Pathogens have always been a major cause of human mortality, so they impose strong
selective pressure on the human genome. Data from population genetic studies, including …

The high prevalence of sickle haemoglobin in Africa shows that malaria has been a major
force for human evolutionary selection, but surprisingly few other polymorphisms have been …

INTRODUCTION Malaria parasites cause human disease by invading and replicating inside
red blood cells. In the case of Plasmodium falciparum, this can lead to severe forms of …