Chemistry, Synthesis, and Structure Activity Relationship of Anticancer Quinoxalines

MF Zayed - Chemistry, 2023 - mdpi.com
Quinoxaline is a fused heterocycle system of a benzene ring and pyrazine ring. It has
earned considerable attention due to its importance in the field of medicinal chemistry. The …

Pharmacological Perspectives of 2‐alkoxy‐3‐Cyanopyridine Scaffolds: An Up‐to‐Date Review

P Mahesha, NS Shetty - ChemistrySelect, 2024 - Wiley Online Library
Abstract The 2‐alkoxy‐3‐cyanopyridine derivatives' straightforward synthesis, ease of
structural manipulation, and variety of intriguing biological activity continue to captivate …

Synthesis of polysubstituted pyridines under combined microwave and ultrasound irradiation: K2CO3-promoted tandem addition/cyclization/hydrogen shift process

H Feng, Y Li, EV Van der Eycken, Y Peng, G Song - Tetrahedron Letters, 2012 - Elsevier
A convenient and efficient K2CO3-promoted tandem reaction of chalcone, malononitrile, and
methanol for the synthesis of highly functionalized pyridines has been developed. This multi …

Synthesis and biological evaluation of new 3-(4-substituted phenyl) aminoquinoxaline derivatives as anticancer agents

MG Thabit, SAA El Bialy, MNA Nasr - Heterocyclic Communications, 2015 - degruyter.com
Quinoxaline derivatives 4–11 were synthesized and evaluated for their in vitro growth
inhibitory activities against liver carcinoma cell line (HEPG2) using the sulforhodiamine B …