The role of the host extracellular matrix (ECM) in infection tends to be neglected. However,
the complex interactions between invading pathogens, host tissues and immune cells occur …

Circulating full-length osteopontin (FL-OPN) is elevated in plasma from patients with various
infectious diseases, such as adult T-cell leukemia, Mycobacterium tuberculosis (TB) …

Tuberculosis (TB) is a deadly infectious disease that affects millions of people globally. TB
proteomics signature discovery has been a rapidly growing area of research that aims to …

Macrophages are large mononuclear phagocytic cells that play a vital role in the immune
response. They are present in all body tissues with extremely heterogeneous and plastic …

Osteopontin (OPN) is a multifunctional phosphorylated protein that is involved in
physiological and pathological events. Emerging evidence suggests that OPN also plays a …

Controlling latent tuberculosis infection (LTBI) is important for preventing tuberculosis (TB).
However, the immune regulation of LTBI remains uncertain. Immune checkpoints and …

Acne is the eighth most frequent disease worldwide. Inflammatory response runs through all
stages of acne. It is complicated and is involved in innate and adaptive immunity. This study …

Objectives Tuberculosis comorbidity with chronic diseases including diabetes, HIV and
chronic kidney disease is of rising concern. In particular, latent tuberculosis infection (LTBI) …

Elevated matricellular proteins (MCPs), including osteopontin (OPN) and galectin-9 (Gal-9),
were observed in the plasma of patients with Manila-type tuberculosis (TB) previously. Here …

Background Mortality rates remain high for human immunodeficiency virus (HIV)–associated
tuberculosis, and our knowledge of contributing mechanisms is limited. We aimed to …