An update on current and novel molecular diagnostics for the diagnosis of invasive fungal infections

JD Jenks, PL White, SE Kidd, T Goshia… - Expert Review of …, 2023 - Taylor & Francis
Background Invasive fungal infections cause millions of infections annually, but diagnosis
remains challenging. There is an increased need for low-cost, easy to use, highly sensitive …

An overview of using fungal DNA for the diagnosis of invasive mycoses

PL White, A Alanio, L Brown, M Cruciani… - Expert Review of …, 2022 - Taylor & Francis
Introduction Fungal PCR has undergone considerable standardization and, together with
the availability of commercial assays, external quality assessment schemes, and extensive …

Emergomycosis, an emerging systemic mycosis in immunocompromised patients: Current trends and future prospects

A Samaddar, A Sharma - Frontiers in Medicine, 2021 - frontiersin.org
Recently, the global emergence of emergomycosis, a systemic fungal infection caused by a
novel dimorphic fungus Emergomyces species has been observed among …

First patient-to-patient intrahospital transmission of clade I Candida auris in France revealed after a two-month incubation period

A Alanio, HM Snell, C Cordier… - Microbiology …, 2022 - Am Soc Microbiol
Candida auris is a recently described emerging pathogen in hospital settings. Five genetic
clades have been delineated, with each clade being isolated from specific geographic …

Histoplasmosis diagnosed in Europe and Israel: a case report and systematic review of the literature from 2005 to 2020

S Antinori, A Giacomelli, M Corbellino, A Torre… - Journal of Fungi, 2021 - mdpi.com
Human histoplasmosis is a mycosis caused by two distinct varieties of a dimorphic fungus:
Histoplasma capsulatum var. capsulatum and H. capsulatum var. duboisii. In Europe, it is …

The “Histoplasmosis Porto Alegre manifesto”—Addressing disseminated histoplasmosis in AIDS

AC Pasqualotto, F Queiroz-Telles… - PLOS Neglected …, 2023 - journals.plos.org
Histoplasmosis is a global fungal disease that has a high prevalence especially in the
Americas caused by diverse species nested within the genus Histoplasma [1]. Other parts of …

Comparison of indirect fungal diagnostic tests in patients with proven histoplasmosis

G Krishnan, M Power, JR Bariola… - Open Forum Infectious …, 2022 - academic.oup.com
Background Histoplasmosis is a common cause of invasive fungal infection in endemic
regions and accurate diagnosis is difficult without direct tissue culture or pathology. Indirect …

A multicentre external quality assessment: A first step to standardise PCR protocols for the diagnosis of histoplasmosis and coccidioidomycosis

D Wilmes, F Hagen, C Verissimo, A Alanio… - Mycoses, 2023 - Wiley Online Library
Background In‐house real‐time PCR (qPCR) is increasingly used to diagnose the so‐called
endemic mycoses as commercial assays are not widely available. Objectives To compare …

Updates on histoplasmosis in solid organ transplantation

JL Saullo, RA Miller - Current Fungal Infection Reports, 2022 - Springer
Abstract Purpose of Review Histoplasmosis remains a challenging infection in solid organ
transplantation. This review provides a topic update with emphasis on the changing …

Molecular Diagnostics for Invasive Fungal Diseases: Current and Future Approaches

D Pham, V Sivalingam, HM Tang, JM Montgomery… - Journal of Fungi, 2024 - mdpi.com
Invasive fungal diseases (IFDs) comprise a growing healthcare burden, especially given the
expanding population of immunocompromised hosts. Early diagnosis of IFDs is required to …