Ovarian cancer is an aggressive disease that is frequently detected at advanced stages and
is initially very responsive to platinum-based chemotherapy. However, the majority of …

Ovarian carcinoma (OC) is an umbrella term for multiple distinct diseases (histotypes), each
with their own developmental origins, clinical behaviour and molecular profile. Accordingly …

Ovarian cancer has the highest mortality of all of the gynecological malignancies. There are
several distinct histotypes of this malignancy characterized by specific molecular events and …

Ovarian clear cell carcinoma (OCCC) is a special pathological type of epithelial ovarian
carcinoma (EOC) and has a high prevalence in Asia without specific molecular subtype …

Our objective was to test whether p53 expression status is associated with survival for
women diagnosed with the most common ovarian carcinoma histotypes (high‐grade serous …

Background Ovarian endometrioid carcinoma (OEC) shares morphological and molecular
features with endometrial endometrioid carcinoma (EEC). Several studies assessed the four …

The first gene therapy product, recombinant adenovirus human p53 (rAd-p53), has been
approved by CFDA since 2013. During these years, most of the clinical trials and the …

Objective Mismatch repair (MMR) deficiency and Bethesda panel microsatellite instability
(MSI) are increasingly analyzed to identify tumors that might benefit from immune checkpoint …

Mullerian clear cell carcinoma (CCC) is often aggressive and chemoresistant. The
prognostic significance of molecular subclassification of endometrioid carcinomas is well …

Recommendations are graded as per the Royal College of Obstetricians and
Gynaecologists document, Clinical Governance Advice No. 1: Guidance for the …