Galectin-9 as a biomarker of disease severity

P Moar, R Tandon - Cellular immunology, 2021 - Elsevier
Abstract Galectin-9 (Gal-9) is a β-galactoside binding lectin known for its immunomodulatory
role in various microbial infections. Gal-9 is expressed in all organ systems and localized in …

Galectin-1: a jack-of-all-trades in the resolution of acute and chronic inflammation

V Sundblad, LG Morosi, JR Geffner… - The Journal of …, 2017 - journals.aai.org
Regulatory signals provide negative input to immunological networks promoting resolution
of acute and chronic inflammation. Galectin-1 (Gal-1), a member of a family of evolutionarily …

Galectin-3 coordinates a cellular system for lysosomal repair and removal

J Jia, A Claude-Taupin, Y Gu, SW Choi, R Peters… - Developmental cell, 2020 - cell.com
Endomembrane damage elicits homeostatic responses including ESCRT-dependent
membrane repair and autophagic removal of damaged organelles. Previous studies have …

Pattern recognition receptors in Drosophila immune responses

Y Lu, F Su, Q Li, J Zhang, Y Li, T Tang, Q Hu… - Developmental & …, 2020 - Elsevier
Insects, which lack the adaptive immune system, have developed sophisticated innate
immune system consisting of humoral and cellular immune responses to defend against …

Glycans as key checkpoints of T cell activity and function

MS Pereira, I Alves, M Vicente, A Campar… - Frontiers in …, 2018 - frontiersin.org
The immune system is highly controlled and fine-tuned by glycosylation, through the
addition of a diversity of carbohydrates structures (glycans) to virtually all immune cell …

Protein glycosylation in extracellular vesicles: Structural characterization and biological functions

J Macedo-da-Silva, VF Santiago… - Molecular …, 2021 - Elsevier
Extracellular vesicles (EVs) are lipid bilayer-enclosed particles involved in intercellular
communication, delivery of biomolecules from donor to recipient cells, cellular disposal and …

[HTML][HTML] A new emerging target in cancer immunotherapy: Galectin-9 (LGALS9)

Y Lv, X Ma, Y Ma, Y Du, J Feng - Genes & Diseases, 2023 - Elsevier
Over the past few decades, advances in immunological knowledge have led to the
identification of novel immune checkpoints, reinvigorating cancer immunotherapy …

Membrane damage and repair: a thin line between life and death

C Barisch, JCM Holthuis, K Cosentino - Biological chemistry, 2023 - degruyter.com
Bilayered membranes separate cells from their surroundings and form boundaries between
intracellular organelles and the cytosol. Gated transport of solutes across membranes …

Tumor resistance mechanisms and their consequences on γδ T cell activation

D Wesch, D Kabelitz, HH Oberg - Immunological reviews, 2020 - Wiley Online Library
Human γδ T lymphocytes are predominated by two major subsets, defined by the variable
domain of the δ chain. Both, Vδ1 and Vδ2 T cells infiltrate in tumors and have been …

Antibacterial potential of a novel Lactobacillus casei strain isolated from Chinese northeast sauerkraut and the antibiofilm activity of its exopolysaccharides

X Xu, Q Peng, Y Zhang, D Tian, P Zhang, Y Huang… - Food & function, 2020 - pubs.rsc.org
Lactobacillus spp., as probiotics, have shown efficacy in the inhibition of pathogenic bacteria
in the intestinal tract. In this study, we investigated the antibacterial activity of Lactobacillus …