Mechano-Chemical Coupling in Hydra Regeneration and Patterning

R Wang, AL Bialas, T Goel… - … and Comparative Biology, 2023 - academic.oup.com
The freshwater cnidarian Hydra can regenerate from wounds, small tissue fragments and
even from aggregated cells. This process requires the de novo development of a body axis …

Large-scale deorphanization of Nematostella vectensis neuropeptide G protein-coupled receptors supports the independent expansion of bilaterian and cnidarian …

D Thiel, LAY Guerra, A Kieswetter, AG Cole… - Elife, 2024 - elifesciences.org
Neuropeptides are ancient signaling molecules in animals but only few peptide receptors
are known outside bilaterians. Cnidarians possess a large number of G protein-coupled …

The cellular basis of feeding-dependent body size plasticity in sea anemones

K Garschall, E Pascual-Carreras… - …, 2024 - journals.biologists.com
Many animals share a lifelong capacity to adapt their growth rates and body sizes to
changing environmental food supplies. However, the cellular and molecular basis …

Microinjection, gene knockdown, and CRISPR-mediated gene knock-in in the hard coral, Astrangia poculata

JF Warner, R Besemer, A Schickle, E Borbee… - …, 2023 - pmc.ncbi.nlm.nih.gov
Cnidarians have become valuable models for understanding many aspects of
developmental biology including the evolution of body plan diversity, novel cell type …

Systemic coordination of whole-body tissue remodeling during local regeneration in sea anemones

S Cheung, D Bredikhin, T Gerber, PJ Steenbergen… - Developmental cell, 2024 - cell.com
The complexity of regeneration extends beyond local wound responses, eliciting systemic
processes across the entire organism. However, the functional relevance and coordination …

A new dawn for the study of cell type evolution

MB Pomaville, SM Sattler, PB Abitua - Development, 2024 - journals.biologists.com
Animal evolution is influenced by the emergence of new cell types, yet our understanding of
this process remains elusive. This prompts the need for a broader exploration across diverse …

[HTML][HTML] A genetic and microscopy toolkit for manipulating and monitoring regeneration in Macrostomum lignano

RN Hall, H Li, C Chai, S Vermeulen, RR Bigasin… - Cell Reports, 2024 - cell.com
Live imaging of regenerative processes can reveal how animals restore their bodies after
injury through a cascade of dynamic cellular events. Here, we present a comprehensive …

[HTML][HTML] CRISPR/Cas9 knock-in methodology for the sea urchin embryo

N Oulhen, S Morita, JF Warner… - Molecular reproduction …, 2023 - ncbi.nlm.nih.gov
CRISPR technology has revolutionized the biological research world, making animals
heretofore recalcitrant to genetic manipulation, accessible to analysis of specific gene …

Mesoscopic axially swept oblique plane microscope for the imaging of freely moving organisms with near-isotropic resolution

S Davis, JR Sommernes, S Hambura… - Biomedical Optics …, 2024 - opg.optica.org
Rapid three-dimensional imaging over extended fields of view (FOVs) is crucial to the study
of organism-wide systems and biological processes in vivo. Selective-plane illumination …

Optimized husbandry and targeted gene-editing for the cnidarian Nematostella vectensis

JE Carvalho, M Burtin, O Detournay, AR Amiel… - …, 2025 - journals.biologists.com
Optimized laboratory conditions for research models are crucial for the success of scientific
projects. This includes controlling the entire life cycle, having access to all developmental …