Most theories of how human cognition is unique propose specific representational
capacities or biases, often thought to arise through evolutionary change. In this Perspective …

Cognitive abilities of the human brain, including language, have expanded dramatically in
the course of our recent evolution from nonhuman primates, despite only minor apparent …

Sequencing-based spatial transcriptomics (ST) is an emerging technology to study in situ
gene expression patterns at the whole-genome scale. Currently, ST data analysis is still …

Throughout evolution, the neocortex has undergone a dramatic expansion providing the
substrate for increasingly complex cognitive abilities, culminating with humans. The …

Otolith organs of the inner ear are innervated by two parallel afferent projections to the
brainstem and cerebellum. These innervations were proposed to segregate across the line …

Mice that are constitutively null for the zinc finger doublesex and mab-3 related (Dmrt) gene,
Dmrt5/Dmrta2, show a variety of patterning abnormalities in the cerebral cortex, including …

Foxg1 expression is highly restricted to the telencephalon and other head structures in the
early embryo. This expression pattern has been exploited to generate conditional knockout …

In the following review, we describe the types of phenotypic changes to the neocortex that
occur over the longer time scale of evolution, and over the shorter time scale of an individual …

Advances in sequencing techniques have made comparative studies of gene expression a
current focus for understanding evolutionary and developmental processes. However …

Establishing appropriate area patterning in the neocortex is a critical developmental event,
and transcription factors whose expression is graded across the developing neural axes …