Neonatal sepsis remains a substantial cause of morbidity and mortality in the nursery
setting. 1 Sepsis in neonates and young infants is challenging to diagnose, because infants …

Background Efforts to develop an evidence-based approach to the evaluation and
management of young febrile infants have spanned more than 4 decades. 1 In the 1970s …

Objectives Identifying infection aetiology is essential for appropriate antibiotic use. Previous
studies have shown that a host-protein signature consisting of TNF-related apoptosis …

Importance Febrile infants at low risk of invasive bacterial infections are unlikely to benefit
from lumbar puncture, antibiotics, or hospitalization, yet these are commonly performed. It is …

We report 2 cases of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
infection (COVID-19) in infants presenting with fever in the absence of respiratory distress …

Welcome to the 29th edition of Nelson's Pediatric Antimicrobial Therapy, the third edition
written during the COVID-19 pandemic, which continues to significantly affect our lives and …

Importance The prevalence of urinary tract infection (UTI), bacteremia, and bacterial
meningitis in febrile infants with SARS-CoV-2 is largely unknown. Knowledge of the …

BACKGROUND: Recent decision rules for the management of febrile infants support the
identification of infants at higher risk of serious bacterial infections (SBIs) without the …

The evaluation and management of young infants presenting with fever remains an area of
significant practice variation. While most well-appearing febrile young infants have a viral …

Methods This was a secondary analysis of quality improvement data collected prospectively
to standardize diagnostic testing for febrile infants≤ 60 days of age at an urban tertiary …