Our objective was to summarise systematically all research evidence related to how patients
value outcomes in chronic obstructive pulmonary disease (COPD). We conducted a …

Chronic obstructive pulmonary disease (COPD) symptoms in the morning, including
dyspnea and sputum production, affect patients' quality of life and limit their ability to carry …

Various medical conditions, disorders, and syndromes exhibit predictable-in-time diurnal
and 24 h patterning in the signs, symptoms, and grave nonfatal and fatal events, eg …

Introduction: Chronic obstructive pulmonary disease (COPD) is a complex and
heterogenous disease that is associated with a range of respiratory and non-respiratory …

Circadian clocks regulate the daily timing of many of our physiological, metabolic and
biochemical functions. The immune system also displays circadian oscillations in immune …

Patients with chronic obstructive pulmonary disease (COPD) exhibit poor sleep quality and
consider morning as the worst time of day for their symptoms. While work has been done to …

Background Although respiratory symptoms are characteristic features of COPD, there is no
standardised method for quantifying their severity in stable disease. Objective To evaluate …

Kronik obstrüktif akciğer hastalığı (KOAH) populasyonda erken ve yüksek bir mortalite,
önemli bir morbidite sebebidir. Sigara KOAH etiyolojisinde en önemli risk faktörü olarak …

There is no single source of compiled data on symptoms experienced by patients with
chronic obstructive pulmonary disease (COPD) when awake and active throughout the day …

Introduction Few studies have examined the 24-h symptom profile in patients with chronic
obstructive pulmonary disease (COPD). The main objective of this study was to determine …